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Title: $The Development of Site-Specific Recombination
Abstract: Site-specific recombinasesSSR have become powerful tools for the integration of target gene into defined chromosomal locus. They have been successfully used both to achieve predictable gene expression in eukaryotic cells and for the systematic creation of transgenic animals. Driven by experimental needs the sophistication and versatility of SSR-based tools have increased tremendously over the past decades through the efforts of numerous investigators.