Publication Information

{'id': 'https://openalex.org/W2359962350', 'doi': None, 'title': 'Cilostazol down-regulates intercellular adhesion molecule-1 expression in kidney in streptozocin-induced diabetic rats', 'display_name': 'Cilostazol down-regulates intercellular adhesion molecule-1 expression in kidney in streptozocin-induced diabetic rats', 'publication_year': 2006, 'publication_date': '2006-01-01', 'ids': {'openalex': 'https://openalex.org/W2359962350', 'mag': '2359962350'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://en.cnki.com.cn/Article_en/CJFDTOTAL-SDYB200601012.htm', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764379641', 'display_name': 'Journal of Shandong University', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4322632810', 'host_organization_name': 'Academic journal of natural science', 'host_organization_lineage': ['https://openalex.org/P4322632810'], 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'https://openalex.org/W2366329984', 'https://openalex.org/W2365620962', 'https://openalex.org/W2365528617', 'https://openalex.org/W2364999022', 'https://openalex.org/W2364036671', 'https://openalex.org/W2363336789', 'https://openalex.org/W2363275981', 'https://openalex.org/W2363143241', 'https://openalex.org/W2359522249', 'https://openalex.org/W2357808024', 'https://openalex.org/W2351670643', 'https://openalex.org/W2348915514'], 'abstract_inverted_index': {'Objective:': [0], 'To': [1], 'investigate': [2], 'the': [3, 17, 225, 237, 244, 248, 254], 'effect': [4, 19], 'of': [5, 13, 20, 28, 45, 51, 65, 76, 83, 86, 100, 120, 138, 154, 203, 206, 231, 236, 250, 256], 'cilostazol': [6, 21, 46, 52, 130, 174, 199], 'on': [7, 22], 'intercellular': [8], 'adhesion': [9], 'molecule-1(ICAM-1)': [10], 'in': [11, 104, 112, 128, 146, 158, 167, 173, 178, 195, 210, 215, 234], 'kidney': [12, 66, 87, 139, 187, 207, 235, 245], 'diabetic': [14, 23, 26, 105, 117, 147, 179, 196, 216, 240, 257], 'rats': [15], 'and': [16, 49, 102, 122, 183, 191, 252], 'protective': [18], 'kidney.Methods:': [24], 'The': [25, 98, 229], 'model': [27], 'male': [29], 'SD': [30, 239], 'rat': [31], 'was': [32, 78, 88, 162, 181, 189, 208], 'prepared': [33], 'by': [34, 80, 90, 96, 246], 'streptozocin(STZ)': [35], 'intraperitoneally.There': [36], 'were': [37, 59, 71, 108], '4': [38], 'groups:': [39], 'normal': [40, 113, 134, 211], 'control': [41, 43, 106, 114, 135, 148, 160, 212, 217], 'group(n=10),diabetic': [42], 'group(n=15),high-dose': [44], 'group(n=15,25': [47], 'mg·kg-1·d-1)': [48], 'low-dose': [50], 'group(n=15,18': [53], 'mg·kg-1·d-1).Treatment': [54], 'for': [55], '12': [56], 'weeks,all': [57], 'animals': [58, 197], 'sacrificed.The': [60], 'fasting': [61], 'blood': [62], 'glucose(BG),HbA1c,the': [63], 'ratio': [64, 137], 'weight': [67, 70, 140, 143], 'to': [68, 141, 222], 'body': [69, 142], 'measured;the': [72], 'ICAM-1': [73, 84, 93, 156, 204, 232, 251], 'mRNA': [74, 157], 'level': [75], 'kindey': [77], 'semi-quantitated': [79], 'RT-PCR;the': [81], 'expression': [82, 153, 230, 249], 'protein': [85, 205], 'detected': [89], 'western': [91, 201], 'blot;the': [92], 'location': [94], 'tested': [95], 'immunofluorescence.Results:': [97], 'levels': [99, 119], 'BG': [101, 121], 'HbA1c': [103, 123], 'group': [107, 161, 180], 'higher': [109, 164], 'than': [110, 165], 'those': [111], 'group(P0.05).Compared': [115], 'with': [116, 133, 198, 227], 'group,the': [118, 136], 'did': [124], 'not': [125], 'decrease': [126, 223], 'significantly': [127, 144, 214], 'both': [129], 'treatment': [131, 151, 226], 'groups.Compared': [132], 'increased': [145], 'group(P0.01)and': [149], 'Cilostazol': [150], 'groups(P0.01).The': [152], 'renal': [155], 'diabeteic': [159], 'significant': [163], 'that': [166], 'other': [168], 'groups,but': [169], 'showed': [170], 'a': [171, 220], 'down-regulation': [172], 'groups(P0.01).By': [175], 'immunofluoescence,ICAM-1': [176], 'staining': [177], 'strong': [182], 'located': [184, 192], 'at': [185], 'fargoing': [186], 'tissues,but': [188], 'weak': [190, 209], 'within': [193], 'limits': [194], 'treatmeat.By': [200], 'blotting,expression': [202], 'group,increased': [213], 'group,and': [218], 'had': [219], 'tendency': [221], 'after': [224], 'cilostazol.Conclusion:': [228], 'increases': [233], 'STZ-induced': [238], 'rat.Cilostazol': [241], 'can': [242], 'protect': [243], 'decreasing': [247], 'delay': [253], 'development': [255], 'nephropathy.': [258]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2359962350', 'counts_by_year': [], 'updated_date': '2024-12-11T13:08:05.648496', 'created_date': '2016-06-24'}