Title: Protective Effect of Weiyanling on Gastric Mucosa of Rats
Abstract: Objective:To investigate the protective effect of Weiyanling on gastric mucosa of rats.Methods: The rats were treated with Weiyanling after receiving absolute ethanol by intragastric intubation. The pathologic changes, inflammation degree, ulcer index (UI) and ulcerous area were observed. Levels of mucosal hexosamine and PGE-2 were measured respectively.Results: Weiyanling significantly decreased UI, ulcerous area and lightened congestion, edema and necrosis (P0.05). There was obvious significance between the treatment group and the model group in the levels of hexosamine and PGE-2 (P0.05). Conclusion: Weiyanling had cytoprotective effects on gastric mucosa in rats. The mechanism of it might inhibit inflammatory action and increase the content of hexosamine and the combination of PGE-2.
Publication Year: 2003
Publication Date: 2003-01-01
Language: en
Type: article
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Cited By Count: 1
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