Title: Progress in cyclophilin A research on viral infectious diseases
Abstract: Cyclophilin A(CyPA),a 20 kD chaperone protein with the peptidylprolyl-cis-trans-isomerase(PPIase)-like activity,is a member of the immunophilin family.CyPA plays an important role in protein folding,signal transduction,oxidative stress,and inflammatory response.In recent years,the research about CyPA mainly focuses on its role in various viral diseases,such as viral hepatitis(HBV/HCV),acquired immunodeficiency syndrome(AIDS) and influenza A H1N1 bird flu(influenza virus A).It is necessary to do further studies to elucidate the role of CypA in viral diseases and the underlying molecular mechanisms.
Publication Year: 2010
Publication Date: 2010-01-01
Language: en
Type: article
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