Title: Influence of borneol on berberine absorption in rat intestine
Abstract: OBJECTIVE To explore the influence of borneol on berberine absorption in rat intestine. METHODS Intestines circumfusion in situ experiment was used to study on the change of absorption kinetics of berberine after adding borneol. RESULTS The intestinal absorption kinetics parameters of berberine in the concentration range of 2.5-10.0 mg·kg-1 had no difference (P0.05); After adding low dose of borneol it had no difference (P0.05); the middle and high dose groups had difference in statistics(P0.01); and the middle dose group based on the Chinese medicine theory amount had the maximum difference (P0.01). CONCLUSION Borneol in the appropriate range of concentrations can promote the rat intestinal absorption of berberine.
Publication Year: 2009
Publication Date: 2009-01-01
Language: en
Type: article
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Cited By Count: 2
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