Title: Effect of proliferation and apoptosis on LoVo cells by matrine injections in vitro
Abstract: AIM:To investigate the effect of proliferation and apoptosis on LoVo cells by matrine injections in vitro.METHODS:The inhibition of Matrine injections on Lovo cells was detected by trypanblau staining and MTT.Fluorescence microscopy and flow cytometry were applied to study cell apoptosis of LoVo cells.RESULTS:Matrine infections inhibited the proliferation of LoVo cells in a dose-dependent manner.After treated by matrine,cell apoptosis peak was observed by flow cytometry.The apoptosis rate was(7.3±1.5)% in therapeutic group,higher than that in control group(2.1±0.5)%.CONCLUSION:Matrine injection exerts some anticancer effect,possibly by inhibiting the cell proliferation and inducing the apoptosis.
Publication Year: 2009
Publication Date: 2009-01-01
Language: en
Type: article
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