Title: Effects of "Xuanfu Daizhe Decoction" on Proliferating Cell Nuclear Antigen in Rats of Mixed Reflux Esophagitis
Abstract: Objective To observe the effects of Xuanfu Daizhe Decoction on proliferating cell nuclear antigen(PCNA)in rats of mixed reflux esophagitis.Methods Rat model was made by esophagoduodenostomy.Eighty rats were randomized into normal group,model group,herb group and mosapride group,and then treated with corresponding methods.The esophageal tissues were stained and the PCNA expression was detected by immuno-histochemical method.Results Xuanfu Daizhe Decoction could suppress PCNA expression(P0.01),similar to mosapride(P0.01).Conclusion Xuanfu Daizhe Decoction can reduce the high PCNA expression in esophageal membrane and fight esophageal reflux to treat mixed reflux esophagitis,prevent relapse and canceration.
Publication Year: 2009
Publication Date: 2009-01-01
Language: en
Type: article
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