Title: Comparison on the clinical curative effect and adverse reactions of the domestic vs.imported oxaliplation
Abstract:OBJECTIVE To investigate the efficacy and safity of the domestic vs.imported oxaliplatin applied in advanced colon cancer.METHODS A total of 68 patients with advanced colon cancer were randomly divide...OBJECTIVE To investigate the efficacy and safity of the domestic vs.imported oxaliplatin applied in advanced colon cancer.METHODS A total of 68 patients with advanced colon cancer were randomly divided into 2 groups : domestic oxaliplatin(50 mg) treatment group(the Ai Heng group,n=35) and imported oxaliplatin(50 mg) treatment group(Eloxatin group,n=33).All patients in both groups was adopted FOLFOX4 program(oxaliplatin combined with 5-fluorouracil and folinic acid).The adverse reactions and recent clinical efficacy were observed and a statistical analysis was conducted.RESULTS There were no significant difference in the recent clinical efficacy and chemotherapy-related adverse reactions between the two groups(P0.05).CONCLUSION Domestic oxaliplatin and the imported oxaliplatin are similar in anti-tumor efficacy and adverse reactions.Domestic oxaliplatin is safe and effective for advanced colon cancer.Read More
Publication Year: 2012
Publication Date: 2012-01-01
Language: en
Type: article
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