Title: Adverse drug reaction reports: Review and analysis of 596 cases
Abstract: Objective To analyze 596 ADR( adverse drug reaction,ADR) cases in a hospital from January 2009 to June 2012,to summarize the characteristics and disciplinarian of ADR,in order to provide rational and safe medication for clinical treatment. Methods A retrospective analysis was made of 596 ADR cases of our hospital in the past three and half years. We analyzed the basic situation of route of administration,types of drugs,clinical manifestations and outcome of the situation. Statistical methods were used to analyze the regularity and the cause of ADR. Results Of 596 ADR cases,patients older than 60 years accounted for approximately 16. 8%,which was slightly higher than other groups. The intravenous route of administration caused most common ADR( 74. 2%); the antibiotics caused larghest number of adverse drug reactions( 47. 5%),Target organ statistical results of adverse drug reactions suggested that skin and its appendages were the most common organ involvement( 37. 9%). Conclusions It's important to further strengthen monitoring and reporting of ADR in clinical task. We need to regulate the use of antibiotics. Clinical pharmacists play a major role in ADR monitoring,which can improve rational use of drugs in the clinical practice.
Publication Year: 2014
Publication Date: 2014-01-01
Language: en
Type: article
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