Title: Inhibition of Baicalin on Proliferarion of Hepatoma HepG-2 Cell Line
Abstract:Objective To investigate the inhibition of baicalin on proliferation hepatoma HepG-2 cells.Methods MTT assay was used to examine the effect of baicalin on the proliferation of HepG-2 cell and flow cyt...Objective To investigate the inhibition of baicalin on proliferation hepatoma HepG-2 cells.Methods MTT assay was used to examine the effect of baicalin on the proliferation of HepG-2 cell and flow cytometry was used for the cell cycle distribution.Results Baicalin inhibited the proliferation of HepG-2 cell and the effects were in a time-and-concentration dependent manner.Baicalin could also induce apoptosis,the S phase was arrested and the ratio of apoptosis there was significant difference than that of control group,respectively.Conclusion Baicalin inhibits proliferation of HepG-2 cells via induction of apoptosis and cell cycle arrest.Read More
Publication Year: 2008
Publication Date: 2008-01-01
Language: en
Type: article
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