Title: Observation on the activity of plasma PAF,PAF-AH and PAF-R in unexplained infertillty patients
Abstract: Objective:To investigate the significance of changes of plasma platelet-activating factor(PAF),platelet-activating factor acetylhydrolase(PAF-AH) and platelet-activating factor receptor activity in the nuexplained infertillty patients.Methods:ELISA and other methods were used to detect the activity of plasma platelet-activating factor,platelet-activating factor acetylhydrolase and platelet-activating factor receptor in 20 patients of the unexplained infertillty.Results:The levels of plasma PAF and PAF-R were significantly lower than that of the matched control(P0.01) and the levels of plasma PAF-AH was significantly higher than that of matched control(P0.01).Conclusion:The activity of PAF-AH in the the unexplained infertillty patients was obviously enhanced,while the activity of PAF and PAF-R was markedly reduced,suggesting that the changes of activity of PAF,PAF-AH and PAF-R may play certein role in the pathogenisis of the unexplained infertillty patients.
Publication Year: 2008
Publication Date: 2008-01-01
Language: en
Type: article
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