Publication Information

Basic Information

Access and Citation

AI Researcher Chatbot

Get quick answers to your questions about the article from our AI researcher chatbot

Primary Location

Authors

Topics

Keywords

Related Works

Title: $Efficacy of Mirtazapine and Sertraline in the Treatment of Depression with Anxiety Symptoms
Abstract: Objective:To compare the clinical effects and adverse reactions of mirtazapine and sertraline in the treatment of depression associated with anxiety. Methods:One hundred and eleven patients depression associated with anxiety were divided into 2 groups: Fifty-six patients (M30, F26, age 39.4±13.7) were treated with mirtazapine, 30~45mg, po, qd for 6wk;; fifty-five patients (M29, F26, age 40.2±12.6) were treated with sertraline, 50~100mg, po, qd for 6wk. Results:The marked effective rate of mirtazapine group and sertraline group were 73.2% and 67.3% (P0.05) in treating depression symptoms, but the marked effective rate of mirtazapine group and sertraline group were 78.8% and 43.6% (P0.05) in treating anxiety symptoms. The adverse reactions in mirtazapine group and sertraline group should no significant difference. Conclusion:Mirtazapine and sertraline is a safe and effective drug for treatment of depression, but mirtazapine is superior to sertraline in reducing anxiety symptoms.