Title: Current status and prospects of liver xenotransplantation
Abstract: Procurement of organs from pig can be a novel means to resolve the shortage of donor organs. With the in-depth study of xenograft rejection and zoonotic infectious diseases, the development of a-1,3-galactosyltransferase gene-knockout(GTKO) pigs promote the translation of xenotransplantation from bench to bedside. However, compared with the heart and renal xenotransplantation, the outcome of liver xenotransplantation is still very limited. The longest survival reported was only 14 d. This paper reviews the key issues and possible solutions which may be confronted in the clinical liver xenotransplantation. We hope to provide reference for the further study.
Publication Year: 2014
Publication Date: 2014-01-01
Language: en
Type: article
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