Title: Diagnostic value of interferon gamma release assay to active pulmonary tuberculosis
Abstract: Objective To evaluate the diagnostic value of interferon gamma release assay to active pulmonary tuberculosis.Methods The interferon gamma release assay based on enzyme linked immunospot assay was performed in 75 patients with suspected active pulmonary tuberculosis.And the result was compared with tuberculosis culture.Results The sensitivity,specificity and accuracy of interferon gamma release assay were 81.1%,90.9% and 84.0%,respectively.The sensitivity of interferon gamma release assay was higher than that of tuberculosis culture(P0.01).Among 23 cases of negative culture results,16 cases were detected positive by interferon gamma release assay.Conclusion Interferon gamma release assay is highly sensitive,specific and helpful to the early and rapid detection of active pulmonary tuberculosis.
Publication Year: 2011
Publication Date: 2011-01-01
Language: en
Type: article
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