Title: Comparison of the efficacy between Ziprasidone and Risperidone treatment for Schizophrenia
Abstract:Objective To discuss the clinical efficacy and side effects of the Ziprasidone and Risperidone treatment for the Schizophrenia,and its impact on patients' quality of life.Methods 98 patients with Schi...Objective To discuss the clinical efficacy and side effects of the Ziprasidone and Risperidone treatment for the Schizophrenia,and its impact on patients' quality of life.Methods 98 patients with Schizophrenia were randomly divided into two groups,49 cases in each group,and were treated by the Ziprasidone(ziprasidone groups) and Risperidone(risperidone group),and to evaluate the clinical efficacy with the positive and negative syndrome scale(PANSS),used the treatment emergent symptom scale(TESS) and laboratory tests to assess the untoward reaction,and used the Schizophrenia quality of life scale(SQLS) to assess patient's quality of life.Results After 8 weeks,the total reduction rate of the PANSS in two groups had no different statistically significance(P0.05);the adverse reactions overall incidence of phase also had no different statistical significance(P0.05);but the patient's quality of life of the Ziprasidone group was significantly better than the Risperidone group,and had different statistically significant(P0.01).Conclusions Ziprasidone and Risperidone in the treatment of Schizophrenia has considerable efficacy,and adverse reactions are few,but Ziprasidone in improving the quality of life of patients is significantly superior to Risperidone.Read More
Publication Year: 2012
Publication Date: 2012-01-01
Language: en
Type: article
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