Title: Antibiotic prophylaxis in cholecystectomy performed by open operation
Abstract: Objective:To evaluate the value of antibiotic prophylaxis in cholecystectomy.Methods:In three hospitals 458 patients undergoing cholecystectomy between 1997.1 and 1999.10 were entered into a retrospective audit. Incidence of postoperative wound infection, and of bile cultures growing pathogenic organism were detected in three different prophylactic dose groups.Results:Age greater than 65 years, acute cholecystitis were proved to be risk factors for postoperative wound infections. There was no difference in wound infection rates between a single injection of antibiotic given half an hour before incision and multiple-dose regimens.Conclusion:An adequate prophylactic effect can be expected by a single injection of antibiotic during cholecystectomy, but the routine antibiotic prophylaxis as recommended for biliary surgery in risk groups ,combining with acute cholecystitis, age over 65 years, obstructive jaundice, is still questionable. [FK(W1。5]
Publication Year: 2000
Publication Date: 2000-01-01
Language: en
Type: article
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