Title: Observation of optic nerve tissue pressure of indirect optic nerve injuries in rabbits
Abstract: Objective [WT5”BZ]To determine the role of optic nerve swelling in secondary damage of optic nerve by measuring the tissue pressure of intraorbital optic nerve of injured and normally controlled eyes of rabbits. [WT5”HZ]Methods Micropipette connected with a pressure transducer was placed in a micromanipulator.Twenty-four hours after injury,the pipette was inserted into intraorbital optic nerve tissue approximately 2mm behind the globe to measure the tissue pressure,and the average pressure from 40 to 60 min after recording was compared and analyzed. Results Twenty-four hours after injury,the pressure of the injured optic nerve tissue (0.315 ±0.334 kPa, n =12) was significantly higher than that of the normal control(-0.085±0.213 kPa, n =12 ; P 0.01). Conclusions When the injured optic nerve tissue pressure increases significantly, surgical decompression of the injured optic nerve should be considered.
Publication Year: 2000
Publication Date: 2000-01-01
Language: en
Type: article
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Cited By Count: 1
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