Title: Intervention of Tianning Decoction on Hemorheology and TNF - α Level in Patients with Migraine
Abstract: Objective:Through the observation of the intervention of different dosages of Tianning Decoction on hemorheology and TNF-α level in patients with migraine to learn the mechanism of wind,phlegm and blood stasis on treating migraine.Methods:126 patients of migraine were randomly divided into normal dose group,high dose group and control group.The normal dose group and high dose group were treated with Tianning Decoction,and the control group were treated with flunarizine hydrochloride capsules.Results:(1) TNF-α and hemorheology after treatment,the difference between the treatment groups and the control group was significant,P 0.01,P 0.05.While the comparison between the treatment groups had no difference except for blood viscosity at the low shear rate and indexes of erythrocyte aggregation,P 0.05.(2) There were no obvious adverse reactions in the three groups during treatment.Conclusion:Tianning Decoction can reduce plasma viscosity and the level of TNF-α to improve the symptoms of migraine.There were no significant differences between normal dose and high dose of Tianning Decoction in the total clinical effects.
Publication Year: 2013
Publication Date: 2013-01-01
Language: en
Type: article
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