Title: Idiopathic pulmonary fibrosis:a review of clinical findings and disgnosis in fifty-one patients
Abstract:Objective To describe and analyze the clinical,characteristics idiopathic pulmonary fibrosis(IPF).Methods A re trospective review of 51 IPF patients,diagnosed between Jan 1990 and May 2000 was made.Re...Objective To describe and analyze the clinical,characteristics idiopathic pulmonary fibrosis(IPF).Methods A re trospective review of 51 IPF patients,diagnosed between Jan 1990 and May 2000 was made.Results The proportion of IPF patients with respiratory disease increased during the stndy period. Most IPF patients were over fifty years old and had an insidious onset of progressive dyspnea and non productive cough.Inspiratory crackles were noted on ausculatation in most patients and 33% had finger clubbing.The most impressive appearance of their radiography was peripheral reticular opacities,profusing largely at the lung bases.Pulmonary function test was consistent with restrictive impairment and impaired gas exchange.The resting arterial blood gases revealed hypoxemia and respiratory alkalosis. Lung surgical biopsy was made in four patients, showing usual interstitial pneumonia(UIP).All patients had no other interstitial lung contirmed disease by history, physical examination, serological tests or transbronchial lung biopsy/bronchoalveolar lavage.Conclusions The diagnosis of IPF in the presence of a surgical biopsy with usual interstitial pneumonia (UIP) includes the following:(1)Exclusion of other known causes of interstitial lung disease;(2)Abnormal pulmonary function including evidence of restriction and /or impaired gas exchange;(3)Abnormalities on conventional chest radiographs or high resolution CT scans.Read More
Publication Year: 2001
Publication Date: 2001-01-01
Language: en
Type: article
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