Title: Clinical Investigation on Treatment of Chronic Atrophic Gastritis and Precancerous Pathological Changes with Prescriptions for Invigorating Qi, Clearing away Heat and Activating Blood Circulation
Abstract: OBJECTIVE The pathological basis for chronic atrophic gastritis and precancerous pathological changes is qi deficiency, blood stasis and heat accumulation. The prescription for invigorating qi, activating blood circulation and clearing away heat is used in this study to observe its effect in the treatment of chronic atrophic gastritis and precancerous pathological changes, compared with a positive control group treated with Weining Granule. METHOD There were 64 patients in the treatment group and 63 patients in the control group. A course of treatment lasted for 3 months, and the patients were treated for two courses of treatment. RESULT In the treatment group, the effective rates after 3 and 6 months of treatment were 75.0% and 95.3% respectively, which were markedly higher than 52.4% and 63.5% in the control group ( P 0.01). There was no marked difference in the improvement of inflammation between the two groups. The total integral for the feeling of fullness, anorexia, belching and loose stool in the treatment group was markedly lower than that in the control group ( P 0.05). After the treatment, the integrals for atrophy, allotypical hyperplasia, etc. were markedly lower than those before the treatment in the treatment group ( P 0.01) and these integrals become lower also in the control group after the treatment ( P 0.05). Again, the integrals in the treatment group were markedly lower than those in the control group ( P 0.05). CONCLUSION The prescription for invigorating qi, activating blood circulation and clearing away heat is quite effective for the chronic atrophic gastritis and precancerous pathological changes.
Publication Year: 2001
Publication Date: 2001-01-01
Language: en
Type: article
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