Title: Clinical significance of serum SOD,GSH-PX and MDA measurement in kidney transplant patient
Abstract: Objectives To investigate the activity changes of serum SOD,GSH-PX and MDA in kidney transplant patient.Methods The activities of serum SOD,GSH-PX and MDA were measured in 59 cases kidney transplant patient and 20 cases normal group.Results The activities of SOD and GSH-PX were reduced evidently(P0.05,P0.01),however the activity of MDA was rised evidently (P0.01) in the kindeytransplant patient compared to the normal group;The activities of SOD,GSH-PX and MDA had the same changes,but no difference(P0.05) in creatinine normal and rised groups of the kidney transplant patients;The activity of GSH-PX was reduced markedly in 3~12 month group and over 12 month group compared to 1~3 month group in the kidney transplant patient(P0.05),MDA reduced markedly between over 12 month group and 1~3 month group (P0.05),other group had no difference(P0.05),but activity of SOD trend to rise and activity of MDA trend to reduce as the time of kidney tanspantation.Conclusion The measurment of serum SOD,GSH-PX and MDA had important clinical significant in treatment and diagnosis of kieney transplant patient.
Publication Year: 2001
Publication Date: 2001-01-01
Language: en
Type: article
Access and Citation
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot