Title: Survey of Motif Discovery Algorithms in Protein-Protein Interaction Networks
Abstract: Network theory is used to model biological systems by biological networks.Therefore,the concepts,properties,and various methods of network could be applied to understand the evolution and behavior of biological systems.It is a new field of bioinformatics,in particular motifs in protein interaction network have very important biological significance.Motifs are patterns of interconnections occurring in complex networks at numbers that are significantly higher than those in randomized networks.In this paper,give a survey of the up-to-date research work and the methods of motif discovery in protein interaction network.Moreover,also describes the future research prospect in the motif discovery.How to identify large motif and combinate motif with function is a working direction in the future.
Publication Year: 2010
Publication Date: 2010-01-01
Language: en
Type: article
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