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748, 777, 808, 989, 1252, 1413, 1558, 1572, 1682, 1922], 'exceptional': [511, 1456], 'tropism': [512, 2123], 'brain': [515, 535, 618, 696, 747, 863, 883, 901, 999, 1036, 1151, 1191, 1246, 1367, 1431, 1763, 1916], 'that': [516, 545, 569, 689, 736, 852, 923, 973, 1642], 'restores': [517], 'a': [518, 522, 529, 540, 547, 590, 762, 778, 809, 940, 948, 984, 1012, 1021, 1163, 1175, 1185, 1205, 1223, 1363, 1379, 1391, 1426, 1462, 1484, 1486, 1531, 1586, 1631, 1647, 1671, 1997, 2040, 2232, 2250], 'normal': [519, 1089, 1491], 'phenotype': [520, 987], 'in': [521, 660, 681, 697, 745, 794, 827, 843, 898, 912, 1031, 1061, 1075, 1087, 1102, 1142, 1149, 1239, 1300, 1358, 1390, 1459, 1467, 1490, 1522, 1597, 1610, 1619, 1676, 1970, 1994, 2033, 2124, 2165, 2180, 2186, 2195, 2200, 2211, 2216, 2239, 2249], 'mouse': [523, 698, 1041, 1180, 1613], 'model': [524, 950, 1614], 'incontinentia': [526, 1183, 1995, 2043], 'pigmenti': [527], '(IP),': [528], 'severe': [530, 954, 1109, 1186], 'human': [531, 955, 1187], 'genetic': [532, 1188, 1654], 'disorder': [533, 1189, 1655], 'vasculature.': [536, 1192], 'heterogeneous': [541], 'group': [542], 'pathologies': [544, 1395], 'display': [546, 1658], 'common': [548], 'characteristic:': [549, 1718], 'they': [550, 1386], 'traditional': [556], 'pharmacological': [557], 'approaches.': [558], 'This': [559, 803, 1469, 2149], 'is': [560, 589, 856, 968, 1095, 1328, 1577, 2039, 2208], 'largely': [561], 'restraints': [564], 'imposed': [565], 'BBB': [568, 588, 1005, 1073, 1283], 'limit': [570], 'drug': [571], 'distribution': [572], 'neurons': [574, 1842, 2238, 2248], 'glial': [576, 650], 'cells': [577, 623, 651, 886, 1086, 1327, 1371, 1412, 1453], 'central': [580, 1803], 'nervous': [581, 1804], 'system': [582, 684, 842, 1805], '(CNS)': [583], 'upon': [584], 'systemic': [585, 1297, 1360, 1445, 1811, 2127], 'administration.': [586], 'The': [587, 700, 880, 1093, 1144, 1197, 1317, 2045], 'highly': [591], 'selective,': [592], 'active': [593, 1548], 'interface': [594], 'composed': [595], 'mainly': [596], 'vascular': [598], 'cells,': [600, 611, 1697], 'also': [602, 866, 917, 1325, 1546], 'astrocytes': [603], 'pericytes,': [605], 'as': [606, 608, 887, 909, 911, 1113, 1307, 1350, 1378, 1494, 1646, 1708], 'well': [607, 910], 'neurons,': [609], 'microglial': [610], 'smooth': [613], 'muscle': [614, 1312], 'cells.': [615], 'spinal': [620, 914], 'cord,': [621], 'lining': [624], 'entire': [626], 'inner': [627], 'surface': [628, 655, 1474, 1544], 'vessels': [631, 659, 1105, 1228], 'linked': [633], 'one': [635, 1710], 'another': [636, 1714], 'tight': [638], 'junctions,': [639], 'inhibit': [641], 'transport': [642], 'compounds': [645], 'across': [646], 'BBB.': [648], 'Astrocyte': [649], 'envelop': [652], 'outer': [654], 'small': [657], 'CNS': [662, 1410, 1443, 2081], 'impose': [664], 'further': [665], 'restrictions.': [666], 'apply': [678], 'innovative': [680], 'vivo': [682, 795, 807, 1240, 1359], 'screening': [683], 'isolate': [686], 'AAVs': [688, 1147, 1253, 1686], 'deliver': [691, 1174], 'transgenes': [692], 'specifically': [693], 'models.': [699], 'exploited': [702, 1171], 'AAV2': [704, 760, 774, 1129, 1274], 'library': [705], 'displaying': [706, 728], 'random': [707, 1132], '7-amino': [708], 'acid': [709], 'insertions': [710], 'on': [711, 1135, 1226, 1404, 1541, 1555, 1562], 'capsid': [713, 1137], 'protein,': [714], 'was': [716, 734, 792, 804, 824, 836, 848, 865, 1152, 1170], 'injected': [717, 1140, 1254], 'intravenously': [718, 1141, 2087], 'reiterated': [720, 1155], 'affinity': [721, 751], 'selection': [722, 1156, 1510], 'brain-homing': [724], 'vectors.': [725], 'An': [726], 'AAV': [727, 854, 1319, 1533, 1645, 1657, 1966, 2116], 'NRGTEWD': [730], 'peptide': [731, 782, 1133, 1496, 1659], '(named': [732], 'AAV-BR1)': [733], 'identified': [735, 882, 2182], 'showed': [737], 'high': [738, 742, 1258], 'specificity': [739], 'accompanied': [740, 867], 'transgene': [743, 790, 1177, 1364, 1528, 1575, 1699], 'expression': [744, 791, 2121], 'minimal': [749], '(including': [752], 'liver,': [755, 876, 1309], 'wild-type': [759, 1022, 1076], 'exhibits': [761], 'strong': [763], 'tropism).': [764], 'AAV-BR1': [765, 817, 964, 1018, 1415], 'revealed': [766], 'substantially': [767], 'improved': [768], 'transduction': [769, 1247, 1408, 1963, 2082], 'efficacy': [770, 1047, 1607], 'over': [771], 'AAV-PPS,': [772], 'vector': [775, 1019, 1167, 1320, 1356, 1416, 1650, 1921, 1967], 'functionalized': [776], 'phage': [779], 'display-selected,': [780], 'brain-specific': [781], '(Chen': [783, 1333], 'al,': [785, 980, 1117, 1263, 1267, 1286, 1290, 1294, 1315, 1335], '2009).': [786, 1336], 'Stable': [787], 'detected': [793, 826], '>': [797], '660': [798], 'days': [799], 'luciferase-mediated': [801], 'bioluminescence.': [802], 'confirmed': [805], 'ex': [806], 'relative': [810], 'brain/liver': [811], 'luciferase': [812], 'activity': [813], '1,000': [815], 'compared': [818], '10': [820], 'AAV-PPS': [822, 1332], '(which': [823], 'predominantly': [825], 'heart).': [829], 'Although': [830, 1269], 'AAV-BR1,': [832, 892, 1347], 'like': [833], 'other': [834, 871, 1678], 'AAVs,': [835], 'non-specifically': [837], 'entrapped': [838], 'reticuloendothelial': [841], 'spleen,': [845], 'organ': [847, 1667], 'not': [849, 1071, 1082, 1372, 1505, 1535, 1578, 1680], 'transduced,': [850], 'demonstrating': [851, 922], 'ligand-directed': [853, 1056], 'required': [857], 'full': [859], 'functionality.': [860], 'addition,': [862], 'homing': [864], 'detargeting': [869], 'sensitive': [872], 'sites,': [873, 1051], 'example,': [875, 1273, 1466], 'heart,': [877, 1308], 'kidneys.': [879], 'vessel': [884], 'target': [890, 1441, 1665], 'broadly': [894, 1507], 'transduced': [895, 1238], 'CNS-associated': [896], 'capillaries': [897, 1000], 'various': [899], 'tested': [900], 'areas': [902], '(cerebellum,': [903], 'olfactory': [904], 'bulb,': [905], 'striatum,': [906], 'cerebral': [907, 1383, 1423], 'cortex),': [908], 'cord.': [915], 'They': [916], 'observed': [918, 1251], 'sporadic': [919], 'neuronal': [920, 2162, 2224], 'transduction,': [921, 1557], 'AAV-BR1—at': [924], 'least': [925], 'some': [927, 1270], 'extent—can': [928], 'cross': [929, 1281], 'BBB,': [931, 1438], 'possibly': [932], 'transcytosis': [934], 'through': [935, 1444], 'layer.': [938], 'As': [939, 1483], 'proof-of-concept': [941, 1653], 'toward': [942, 1208], 'medical': [943], 'applications,': [944], 'used': [947], 'murine': [949], 'IP': [952, 967, 1612], '(a': [953], 'disease)': [957], 'evaluate': [959], 'therapeutic': [961, 1176, 1211, 1601], 'effects': [962, 1111, 1218], '(Fig': [965], '1).': [966], 'caused': [969], 'heterozygous': [971, 1033], 'mutations': [972, 2158, 2179], 'inactivate': [974], 'Nemo': [976, 1023, 1069, 1100], '(Smahi': [978], '2000);': [981], 'patients': [982], 'exhibit': [983], 'mild': [985], 'dermal': [986], 'associated': [988, 1681], 'major': [990], 'neurological': [991, 1394, 1929], 'symptoms': [992], 'epilepsy': [994], 'loss': [997], 'disruption': [1002], '(Meuwissen': [1006], 'Mancini,': [1008], '2012).': [1009], 'Injection': [1010], 'single': [1013], 'intravenous': [1014], 'dose': [1015], 'carrying': [1020], '(AAV-BR1-NEMO)': [1025, 1178], 'completely': [1026], 'reversed': [1027], 'abnormalities': [1030], 'both': [1032, 2215], '(Nemo−/+)': [1034], 'cell-conditionally': [1038], 'null': [1039], '(NemobeKO)': [1040], 'models': [1042, 1181], 'IP.': [1044], 'Besides': [1045], 'its': [1046, 1538], 'at': [1048, 1257], 'diseased': [1050, 1091], 'two': [1052], 'aspects': [1053], 'noteworthy': [1060], 'terms': [1062], 'clinical': [1064, 1640, 1703], 'safety:': [1065], '(i)': [1066], 'Overexpression': [1067], 'did': [1070, 1081], 'affect': [1072], 'tightness': [1074], 'animals,': [1077], '(ii)': [1079], 'AAV-BR1-NEMO': [1080, 1609], 'transduce': [1083, 1323, 1695], 'peripheral': [1084], 'either': [1088], 'animals.': [1092], 'latter': [1094], 'particular': [1097], 'relevance': [1098], 'because': [1099], 'upregulation': [1101], 'non-CNS': [1103, 1304], 'lead': [1107, 1165], 'adverse': [1110], 'such': [1112, 1306, 1493, 1530, 1707], 'atherosclerosis': [1114], '(Gareus': [1115], '2008).': [1118, 1316], 'Figure': [1119], '1.': [1120], 'Selection': [1121], 'functional': [1123], 'validation': [1124], 'brain-targeting': [1126], 'AAVsLibraries': [1127], 'expressing': [1131], 'inserts': [1134], 'their': [1136, 1296, 1473, 1690], 'proteins': [1138], 'were': [1139], 'mice.': [1143], 'population': [1145], 'enriched': [1148], 'subjected': [1153], 'rounds,': [1157], 'leading': [1158, 1476], 'identification': [1161], 'candidate': [1164], 'viral': [1166, 1737, 1920], '(AAV-BR1),': [1168], 'selectively': [1173], 'pigmenti,': [1184], 'Download': [1193, 1195], 'figure': [1194], 'PowerPoint': [1196], 'data': [1198], 'promising': [1206], 'step': [1207], 'effective': [1210], 'approaches': [1212], 'targeting': [1213, 1302, 1487, 1585], 'CNS,': [1215], 'where': [1216], 'synergistic': [1217], 'be': [1220, 1237, 1419, 1506, 1516, 1581, 1594, 1662], 'achieved': [1221], 'concomitant': [1224], 'intervention': [1225], 'and,': [1229], 'potentially,': [1230], 'neurons.': [1231], 'Both': [1232, 1551], 'cell': [1233, 1543], 'types,': [1234], 'indeed,': [1235], 'could': [1236, 1417], 'AAV-BR1.': [1242], 'So': [1243], 'far,': [1244], 'has': [1248], 'only': [1249, 1318, 1373, 1536], 'been': [1250], 'locally': [1255], 'doses': [1259], '(de': [1260], 'Backer': [1261, 1723], '2010;': [1264], 'Markakis': [1265, 1941], '2010).': [1268], 'natural,': [1271], 'AAV9,': [1276], 'surface-modified': [1278], 'serotypes': [1279, 1968, 2117], '(Foust': [1284], '2009;': [1287], 'Yang': [1288, 2057], '2014;': [1291], 'Choudhury': [1292, 1779], '2016),': [1295], 'administration': [1298, 1361], 'results': [1299, 1521], 'substantial': [1301], 'tissues': [1305], 'skeletal': [1311], '(Zincarelli': [1313], 'described': [1321, 1498], 'brain—but': [1324], 'cardiac—microvascular': [1326], 'previously': [1330], 'mentioned': [1331], 'However,': [1337, 1448], 'elegantly': [1342], 'demonstrate': [1343], 'enhanced': [1344], 'functionality': [1345], 'identifying': [1348], 'it': [1349], 'first': [1352], 'endothelium.': [1368], 'contribute': [1374], 'BBB:': [1377], 'key': [1380, 1715], 'component': [1381], 'vessels,': [1385], 'functionally': [1388], 'involved': [1389], 'plethora': [1392], 'including': [1396], 'stroke,': [1397, 1427], 'multiple': [1398], 'sclerosis,': [1399], 'epilepsy,': [1400], 'cancer.': [1402, 1468], 'Depending': [1403], 'delivered': [1406, 2088], 'transgene,': [1407], 'tuned': [1420], 'improve': [1422], 'perfusion': [1424], 'after': [1425, 1810, 2126], 'impair': [1428], 'vascularization': [1429], 'tumors,': [1432], 'repair': [1433], 'otherwise': [1435], 'modulate': [1436], 'directly': [1440], 'circulation.': [1447], 'although': [1449], 'genetically': [1450], 'stable,': [1451], 'reveal': [1454], 'phenotypic': [1457], 'plasticity': [1458], 'pathologic': [1460], 'conditions,': [1461, 1492], 'well-described': [1463], 'scenario,': [1464], 'implies': [1470], 'remodeling': [1471], 'proteome,': [1475], 'differential': [1478], 'receptor': [1479, 1540], 'exposure': [1480], 'and/or': [1481], 'accessibility.': [1482], 'consequence,': [1485], 'ligand': [1488], 'selected': [1489, 1663], 'motif': [1497], '(2016),': [1503], 'might': [1504], 'applicable,': [1508], 'disease-specific': [1512], 'addresses': [1513], 'will': [1514], 'probably': [1515], 'necessary': [1517], 'achieve': [1519], 'similar': [1520], 'different': [1523, 1559], 'contexts.': [1524], 'Moreover,': [1525], 'ligand-targeted': [1532], 'must': [1534], 'recognize': [1537], 'undergo': [1547], '(receptor-mediated)': [1549], 'internalization.': [1550], 'events': [1552], 'may': [1553], 'impact': [1554], 'signal': [1556], 'outcomes': [1560], 'depending': [1561], "receptor's": [1564], 'function(s).': [1565], 'Interference': [1566], 'therapy-induced': [1569], 'intracellular': [1570, 2196], 'pathways': [1571], 'desired': [1574], 'effect': [1576], 'expected': [1579], 'when': [1584], 'suicide': [1587], 'cancer': [1590], 'tissues,': [1591], 'should': [1593], 'carefully': [1595], 'evaluated': [1596], 'case': [1599], 'genes.': [1602], 'regard,': [1605], 'represents': [1615], 'encouraging': [1617], 'result': [1618, 2194], 'light': [1620], 'future': [1622], 'applications.': [1623], 'conclusion,': [1625], 'pioneering': [1632], 'work': [1633], 'address': [1635], 'very': [1636], 'relevant': [1637, 1717], 'unmet': [1639], 'needs': [1641], 'go': [1643], 'beyond': [1644], 'investigated.': [1656], 'libraries': [1660], 'any': [1666], 'interest,': [1669], 'providing': [1670], 'valuable': [1672], 'strategy': [1673], 'applications': [1675], 'many': [1677], 'diseases': [1679], 'system.': [1685], 'recognized': [1688], 'low': [1691], 'immunogenicity,': [1692], 'ability': [1693], 'non-dividing': [1696], 'expression,': [1700], 'non-pathogenicity,': [1701], 'safety.': [1704], 'Surface-engineered': [1705], 'vectors,': [1706], 'discovered': [1711], 'here,': [1712], 'add': [1713], 'clinically': [1716], 'unprecedented': [1719], 'specificity.': [1720], 'References': [1721], 'de': [1722, 1871], 'MW,': [1724], 'Brans': [1725], 'Luijendijk': [1727], 'MC,': [1728], 'Garner': [1729], 'KM,': [1730], 'Adan': [1731], 'RA': [1732], '(2010)': [1733, 1961], 'Optimization': [1734], 'vector-mediated': [1738], 'hypothalamus.': [1743, 2228], 'Hum': [1744], 'Ther': [1746, 1818, 1981, 2099, 2130], '21:': [1747], '673–682CrossrefPubMedWeb': [1748], 'Science®Google': [1750, 1777, 1822, 1851, 1890, 1939, 1985, 2006, 2055, 2103, 2134], 'Scholar': [1751, 1778, 1823, 1852, 1891, 1940, 1986, 2007, 2056, 2104, 2135], 'Chen': [1752], 'YH,': [1753], 'Chang': [1754], 'M,': [1755, 1907, 1909], 'Davidson': [1756], 'BL': [1757], '(2009)': [1758, 1836], 'signatures': [1760], 'disease': [1762], 'endothelia': [1764], 'new': [1766], 'sites': [1767], 'CNS-directed': [1769], 'enzyme': [1770], 'therapy.': [1771], 'Nat': [1772, 1846], '15:': [1774], '1215–1218CrossrefCASPubMedWeb': [1775], 'SR,': [1780], 'Harris': [1781], 'AF,': [1782], 'Cabral': [1783], 'DJ,': [1784, 2066], 'Keeler': [1785], 'AM,': [1786], 'Sapp': [1787], 'E,': [1788, 1827, 1856], 'Ferreira': [1789], 'JS,': [1790], 'Gray-Edwards': [1791], 'HL,': [1792], 'Johnson': [1793, 1795], 'JA,': [1794], 'AK,': [1796], 'Su': [1797, 2069], 'Q': [1798], 'Widespread': [1802], 'transfer': [1807], 'silencing': [1809], 'novel': [1814], 'AAV-AS': [1815], 'vector.': [1816], '24:': [1819], '726–735CrossrefCASPubMedWeb': [1820], 'Foust': [1824], 'KD,': [1825], 'Nurre': [1826], 'Montgomery': [1828], 'CL,': [1829], 'Hernandez': [1830], 'A,': [1831, 1868, 1901, 2009, 2019, 2021], 'Chan': [1832], 'CM,': [1833], 'Kaspar': [1834], 'BK': [1835], 'Intravascular': [1837], 'AAV9': [1838], 'preferentially': [1839], 'targets': [1840], 'neonatal': [1841], 'adult': [1844, 2084], 'astrocytes.': [1845], 'Biotechnol': [1847], '27:': [1848], '59–65CrossrefCASPubMedWeb': [1849], 'Gareus': [1853], 'R,': [1854, 1866], 'Kotsaki': [1855], 'Xanthoulea': [1857], 'S,': [1858, 1897, 1948, 2015, 2017, 2060, 2108], 'van': [1859], 'der': [1860], 'Made': [1861], 'I,': [1862], 'Gijbels': [1863], 'MJJ,': [1864], 'Kardakaris': [1865], 'Polykratis': [1867], 'Kollias': [1869], 'G,': [1870, 1895, 2011, 2110], 'Winther': [1872], 'MPJ,': [1873], 'Pasparakis': [1874, 1908], 'M': [1875], '(2008)': [1876, 2113], 'Endothelial': [1877], 'cell-specific': [1878, 1919], 'NF-[kappa]B': [1879], 'inhibition': [1880], 'protects': [1881], 'mice': [1882, 2085, 2125, 2217], 'atherosclerosis.': [1884], 'Cell': [1885], 'Metab': [1886], '8:': [1887, 1934], '372–383CrossrefCASPubMedWeb': [1888], 'J,': [1893, 1903, 1946, 1952, 2072], 'Dogbevia': [1894], 'Michelfelder': [1896], 'Ridder': [1898], 'DA,': [1899], 'Hunger': [1900], 'Wenzel': [1902], 'Seismann': [1904], 'H,': [1905, 2062], 'Lampe': [1906], 'Kleinschmidt': [1910], 'JA': [1911], 'A': [1915], 'microvasculature': [1917], 'potential': [1924], 'diseases.': [1930], '609–625Wiley': [1935], 'Online': [1936], 'LibraryCASPubMedWeb': [1937], 'EA,': [1942], 'Vives': [1943], 'KP,': [1944], 'Bober': [1945], 'Leichtle': [1947], 'Leranth': [1949], 'C,': [1950, 2068, 2106], 'Beecham': [1951], 'Elsworth': [1953], 'JD,': [1954], 'Roth': [1955], 'RH,': [1956], 'Samulski': [1957], 'RJ,': [1958], 'Redmond': [1959], 'DE': [1960], 'Comparative': [1962], 'efficiency': [1964], '1-6': [1969], 'substantia': [1972], 'nigra': [1973], 'striatum': [1975], 'primate': [1978], '18:': [1982], '588–593CrossrefCASPubMedWeb': [1983], 'Meuwissen': [1987], 'ME,': [1988], 'Mancini': [1989], 'GM': [1990], '(2012)': [1991], 'Neurological': [1992], 'findings': [1993], 'pigmenti;': [1996], 'review.': [1998], 'Eur': [1999], 'Genet': [2002], '55:': [2003], '323–331CrossrefPubMedWeb': [2004], 'Smahi': [2008], 'Courtois': [2010], 'Vabres': [2012], 'P,': [2013], 'Yamaoka': [2014], 'Heuertz': [2016], 'Munnich': [2018], 'Heiss': [2022], 'NS,': [2023], 'Klauck': [2024], 'SM,': [2025], 'Kioschis': [2026], 'P': [2027], '(2000)': [2030], 'Genomic': [2031], 'rearrangement': [2032], 'NEMO': [2034], 'impairs': [2035], 'NF-kappaB': [2036], 'activation': [2037], 'cause': [2041], 'pigmenti.': [2044], 'International': [2046], 'Incontinentia': [2047], 'Pigmenti': [2048], '(IP)': [2049], 'Consortium.': [2050], 'Nature': [2051], '405:': [2052], '466–472CrossrefCASPubMedWeb': [2053], 'B,': [2058], 'Li': [2059], 'Wang': [2061], 'Guo': [2063], 'Y,': [2064], 'Gessler': [2065], 'Cao': [2067], 'Q,': [2070], 'Kramer': [2071], 'Zhong': [2073], 'L,': [2074], 'Ahmed': [2075], 'SS': [2076], '(2014)': [2079], 'Global': [2080], 'rAAVrh.': [2089], '8': [2090], 'rAAVrh.10': [2092], 'nonhuman': [2094], 'primates': [2095], 'rAAVrh.10.': [2097], '22:': [2100], '1299–1309CrossrefCASPubMedWeb': [2101], 'Zincarelli': [2105], 'Soltys': [2107], 'Rengo': [2109], 'Rabinowitz': [2111], 'JE': [2112], 'Analysis': [2114], '1–9': [2118], 'mediated': [2119], 'injection.': [2128], '16:': [2131], 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'secretion': [2202], 'mutant': [2204], 'proteins.': [2205], 'mRNA': [2207], 'strongly': [2209], 'expressed': [2210], 'embryonic': [2212], 'nasal': [2213], 'mesenchyme': [2214], 'humans,': [2219], 'during': [2220], '(GnRH)': [2223], 'knockdown': [2230], 'causes': [2231], 'reduced': [2233], 'immature': [2236], 'GnRH': [2237, 2247], 'vitro,': [2240], 'perturb': [2242], 'extension': [2245], 'gnrh3:EGFP': [2251], 'zebrafish': [2252], 'model.': [2253], 'Scientific': [2254], 'images': [2255], 'Valentina': [2257], 'André,': [2258], 'Pharmacological': [2261], 'Biomolecular': [2263], 'Sciences,': [2264], 'Milan,': [2267, 2268], 'Centre': [2273], 'Endocrinology,': [2275], 'William': [2276], 'Harvey': [2277], 'Institute,': [2279], 'Barts': [2280], 'London': [2283], 'Medicine': [2286], 'Dentistry,': [2288], 'Queen': [2289], 'Mary': [2290], 'London,': [2293, 2294], 'UK.': [2295], '(Artistic': [2296], 'rendition': [2297], 'Uta': [2299], 'Mackensen)': [2300], 'Volume': [2301], '8Issue': [2302], '61': [2303], 'June': [2304], '2016In': [2305], 'FiguresReferencesRelatedDetailsLoading': [2308], '...': [2309]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2352862165', 'counts_by_year': [{'year': 2023, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 3}, {'year': 2020, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 3}, {'year': 2017, 'cited_by_count': 1}], 'updated_date': '2024-12-15T09:03:38.973826', 'created_date': '2016-06-24'}