Title: Comparative study between aripiprazole and olanzapine in the treatment of schizophrenia.
Abstract: Objective To investigate the efficacy and quality of life in schizophrenic patients treated by aripiprazole and olanzapine.Methods A total of 68 patients with schizophrenia were randomly divided into aripiprazole group and olanzapine group for 8-week treatment.Positive and Negative Symptoms Scale(PANSS)was used to evaluate the clinical efficacy,Treatment Emergent Symptom Scale(TESS)for side effects and General Quality of Life Inventory(GQOLI-74)for quality of life. Results The patients in both groups had significant clinical efficacy,and the two drugs obviously improved the quality of life.There were no significant differences in the efficacy and quality of life(P0.05) between the two groups.The side effects of aripiprazole were insomnia and headache,and those of olanzapine were weight gain and increased blood glucose.Conclusion Aripiprazole and olanzapine are similar in the treatment of schizophrenia with fewer side effects,and they both improve quality of life.
Publication Year: 2009
Publication Date: 2009-01-01
Language: en
Type: article
Access and Citation
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot