Title: Analysis of genotypes of hantavirus isolates in Hangzhou
Abstract: Objective:To study the genotypes of hantavirus carrying Rodent in Hangzhou.Methods:Four hantavirus strains,which were positive by antigen immunofluorescence assay,were analyzed by reverse transcription polymerase chain reaction(RT-PCR),nucleotide sequence and cell culture.Results:Two cell lesions sequence revealed that the segment M belongs to seoul virus.The homology of segment M was above 85% between this seoul virus and other seoul virus,and was 70% between this seoul virus and Hantaan virus.Genotype of two hantavirus strains was S3 sub-type of seoul virus,whose homology with BjHD01(DQ133505)was 99%.Conclusion:S3 sub-type of seoul virus is probably the main Genotypes of hantavirus strains in Hangzhou.
Publication Year: 2009
Publication Date: 2009-01-01
Language: en
Type: article
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