Title: HPLC Analysis on Stability of N-(2-Methoxyethyl)-2-(3-Nitro -1,2,4-Triazole-1-)Acetamide in Frozed Injection
Abstract: N-(2-Methoxyethyl)-2-(3-Nitro-1,2,4-Triazole-1)-Acetamide is a new radiosensitizer. A HPLC method of N-(2-Methoxyethyl)-2-(3-Nitro-1,2,4-Triazole-1-)Acetamide injection was established. On the base of this method, the changes of N-(2-Methoxyethyl)- 2-(3-Nitro-1,2,4-Triazole-1-)Acetamide in frozed injection have been observed. Different concentration samples of N-(2-Methoxyethyl)-2-(3-Nitro-1,2,4-Triazole-1-)Acetamide were determined with HPLC. The peak area and concentration of N-(2-Methoxyethyl)-2-(3-Nitro -1,2,4-Triazole-1-)Acetamide showed fine linearity. N-(2-Methoxyethyl)-2-(3-Nitro-1,2,4- Triazole-1-)Acetamide in frozed injection was steady. The results showed that the stability of N-(2-Methoxyethyl)-2-(3-Nitro-1,2,4-Triazole-1-)Acetamide in frozed injection was very well.
Publication Year: 2007
Publication Date: 2007-01-01
Language: en
Type: article
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