Title: Clinical utiligy of pharmacological stress myocardial perfusion imaging in cardiac syndrome X
Abstract: Objective:To evaluate the comparative value of dipyridamole 201Tl single photon emission computer tomgraphy(SPECT) cardiac perfusion imaging and dobutamine 99mTc-MIBI SPECT imaging in cardiac syndrome X(CSX).Methods:A cohort of seventy-four patients with known CSX who had undergone pharmacological stress myocardial perfusion imaging in our hospital from March 2005 to April 2012 were reviewed.The CSX patients were assigned to group A and group B according to different pharmacological stress agents.Group A underwent dipyridamole 201Tl SPECT cardiac imaging and group B underwent dobutamine 99mTc-MIBI SPECT imaging.Images were interpreted by more than two experienced nuclear medicine physicians.Comparisons of the categorical variables between the two groups were performed using χ2 test for positive rates.Results:In group A,reverse redistribution phenomena were observed in 45 cases,while the remaining 8 had normal cardiac imaging.In group B,only 3 cases had reversible defect.The positive rates were 84.91%(in group A,45/53)and 14.29%(in group B,3/21),respectively.There was statistically significant difference in positive rate between the two groups(χ2=29.89,P0.001).Conclusion:Reverse redistribution in dipyridamole 201Tl SPECT cardiac imaging may be of some value for the assessment of patients with CSX.
Publication Year: 2013
Publication Date: 2013-01-01
Language: en
Type: article
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