Title: Measurement and analysis of cervico-medullary angle of patients with Chiari type 1 malformation on 1.5T MR imaging
Abstract: Objective: To determine the angle between medulla oblongata and upper spinal cord on midsagittal MRI in normal Chinese individuals and patients with Chiari type 1 malformation to provide a clinical reference and study their clinical significance by MRI.Methods: 126 Chinese with no evidence of CNS abnormity and 20 patients with Chiari type 1 malformation diagnosed by X-ray film were studied by MRI.The measurement was performed on the central sagittal slice.Results: The normal cervico-medullary angle had a minimum of 156°,maximum of 173.9° and mean angle of 166.2° with the 95% confidence interval of 159.77°~171.14°.The estimating range of the angle of the Chiari type 1 malformation patients group had a minimum of 159.9°and maximum of 173.2° with the 95% confidence interval of 160.25°~172.02°.Normal group and the size of the angle difference between the case group were significant in the referential range of the normal natural angle between medulla oblongata and upper spinal cord(P=0.000).Conclusion: For the diagnosis of Chiari type 1 malformation,MR can directly display the medulla oblongata pons and cerebellum herniation pressure situation,which has reference value for the above to make the correct diagnosis of the disease in MRI imaging.
Publication Year: 2011
Publication Date: 2011-01-01
Language: en
Type: article
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