Title: The Influences of insulin-like growth factor-I and Simvastatin on the proliferation of human lung fibroblast
Abstract: Objective Study on the influences of Simvastatin and IGF-1 on the proliferation of human lung fibroblast.Methods human lung fibroblast was cultured and MTT colorimetry assay was used to determine the proliferation of human lung fibroblast,the influences of IGF-1 and Simvastatin on the proliferation of human lung fibroblast was observed in vitro.Results The proliferation of human lung fibroblast was inhibited by Simvastatin.Combination of IGF-1 and Simvastatin can inhibit the proliferative capability of human lung fibroblast.Conclusion Simvastatin potently inhibited while IGF-I stimulate human lung fibroblast proliferation.
Publication Year: 2009
Publication Date: 2009-01-01
Language: en
Type: article
Access and Citation
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot