Publication Information

{'id': 'https://openalex.org/W2349674900', 'doi': None, 'title': 'Effect of PARP inhibitors on the proliferation inhibition by cisplatin in lung cancer cell lines', 'display_name': 'Effect of PARP inhibitors on the proliferation inhibition by cisplatin in lung cancer cell lines', 'publication_year': 2012, 'publication_date': '2012-09-14', 'ids': {'openalex': 'https://openalex.org/W2349674900', 'mag': '2349674900'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://en.cnki.com.cn/Article_en/CJFDTOTAL-QLZL201217004.htm', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764348286', 'display_name': 'Zhonghua zhongliu fangzhi zazhi', 'issn_l': '1673-5269', 'issn': ['1673-5269'], 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4323238127', 'host_organization_name': 'Zhonghua Zhong liu Fang Zhi za Zhi', 'host_organization_lineage': ['https://openalex.org/P4323238127'], 'host_organization_lineage_names': ['Zhonghua Zhong liu Fang Zhi za Zhi'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': [], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5036263606', 'display_name': 'Jun Ling Liu', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Jun Ling Liu', 'raw_affiliation_strings': ['Sun-Yat-Sen University'], 'affiliations': [{'raw_affiliation_string': 'Sun-Yat-Sen University', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5063211767', 'display_name': 'Rui Sun', 'orcid': 'https://orcid.org/0000-0002-5616-6849'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Rui Sun', 'raw_affiliation_strings': ['Sun-Yat-Sen University'], 'affiliations': [{'raw_affiliation_string': 'Sun-Yat-Sen University', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5074279206', 'display_name': 'Wan Hu Li', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210163399', 'display_name': 'Shandong First Medical University', 'ror': 'https://ror.org/05jb9pq57', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I4210163399']}, {'id': 'https://openalex.org/I4210100830', 'display_name': 'Shandong Tumor Hospital', 'ror': 'https://ror.org/01413r497', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210100830']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Wan Hu Li', 'raw_affiliation_strings': ['Shandong Cancer Hospital'], 'affiliations': [{'raw_affiliation_string': 'Shandong Cancer Hospital', 'institution_ids': ['https://openalex.org/I4210163399', 'https://openalex.org/I4210100830']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100445266', 'display_name': 'Yu Wang', 'orcid': 'https://orcid.org/0000-0002-7309-7304'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Yu Wang', 'raw_affiliation_strings': ['Sun-Yat-Sen University'], 'affiliations': [{'raw_affiliation_string': 'Sun-Yat-Sen University', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5111531022', 'display_name': 'Xiu Yu Cai', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Xiu Yu Cai', 'raw_affiliation_strings': ['Sun-Yat-Sen University'], 'affiliations': [{'raw_affiliation_string': 'Sun-Yat-Sen University', 'institution_ids': []}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5072577051', 'display_name': 'Wen Jiang', 'orcid': 'https://orcid.org/0000-0003-1086-3603'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Wen Qi Jiang', 'raw_affiliation_strings': ['Medical Oncology'], 'affiliations': [{'raw_affiliation_string': 'Medical Oncology', 'institution_ids': []}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': False, 'cited_by_count': 0, 'citation_normalized_percentile': {'value': 0.0, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 0, 'max': 64}, 'biblio': {'volume': '19', 'issue': '17', 'first_page': '1290', 'last_page': '1293'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11914', 'display_name': 'PARP inhibition in cancer therapy', 'score': 0.9897, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11914', 'display_name': 'PARP inhibition in cancer therapy', 'score': 0.9897, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/parp-inhibitor', 'display_name': 'PARP inhibitor', 'score': 0.52703506}, {'id': 'https://openalex.org/keywords/growth-inhibition', 'display_name': 'Growth inhibition', 'score': 0.50012064}, {'id': 'https://openalex.org/keywords/mtt-assay', 'display_name': 'MTT assay', 'score': 0.48196575}], 'concepts': [{'id': 'https://openalex.org/C2778239845', 'wikidata': 'https://www.wikidata.org/wiki/Q412415', 'display_name': 'Cisplatin', 'level': 3, 'score': 0.9340479}, {'id': 'https://openalex.org/C182979987', 'wikidata': 'https://www.wikidata.org/wiki/Q3907241', 'display_name': 'Poly ADP ribose polymerase', 'level': 4, 'score': 0.805205}, {'id': 'https://openalex.org/C2776256026', 'wikidata': 'https://www.wikidata.org/wiki/Q47912', 'display_name': 'Lung cancer', 'level': 2, 'score': 0.56401944}, {'id': 'https://openalex.org/C62112901', 'wikidata': 'https://www.wikidata.org/wiki/Q189159', 'display_name': 'Cell growth', 'level': 2, 'score': 0.5632447}, {'id': 'https://openalex.org/C81885089', 'wikidata': 'https://www.wikidata.org/wiki/Q189082', 'display_name': 'Cell culture', 'level': 2, 'score': 0.54382944}, {'id': 'https://openalex.org/C2779138821', 'wikidata': 'https://www.wikidata.org/wiki/Q7118227', 'display_name': 'PARP inhibitor', 'level': 5, 'score': 0.52703506}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.5195423}, {'id': 'https://openalex.org/C2779707156', 'wikidata': 'https://www.wikidata.org/wiki/Q5611758', 'display_name': 'Growth inhibition', 'level': 3, 'score': 0.50012064}, {'id': 'https://openalex.org/C2780783641', 'wikidata': 'https://www.wikidata.org/wiki/Q738686', 'display_name': 'MTT assay', 'level': 3, 'score': 0.48196575}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.41931936}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.3996707}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.39461213}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.33506355}, {'id': 'https://openalex.org/C2776694085', 'wikidata': 'https://www.wikidata.org/wiki/Q974135', 'display_name': 'Chemotherapy', 'level': 2, 'score': 0.244885}, {'id': 'https://openalex.org/C82381507', 'wikidata': 'https://www.wikidata.org/wiki/Q416878', 'display_name': 'Polymerase', 'level': 3, 'score': 0.21021271}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.17539471}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.16961089}, {'id': 'https://openalex.org/C552990157', 'wikidata': 'https://www.wikidata.org/wiki/Q7430', 'display_name': 'DNA', 'level': 2, 'score': 0.1339272}, {'id': 'https://openalex.org/C143998085', 'wikidata': 'https://www.wikidata.org/wiki/Q162555', 'display_name': 'Oncology', 'level': 1, 'score': 0.12429476}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.05454737}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://en.cnki.com.cn/Article_en/CJFDTOTAL-QLZL201217004.htm', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764348286', 'display_name': 'Zhonghua zhongliu fangzhi zazhi', 'issn_l': '1673-5269', 'issn': ['1673-5269'], 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4323238127', 'host_organization_name': 'Zhonghua Zhong liu Fang Zhi za Zhi', 'host_organization_lineage': ['https://openalex.org/P4323238127'], 'host_organization_lineage_names': ['Zhonghua Zhong liu Fang Zhi za Zhi'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.58}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W3174662263', 'https://openalex.org/W3013413945', 'https://openalex.org/W2983763811', 'https://openalex.org/W2883344686', 'https://openalex.org/W2594860415', 'https://openalex.org/W2588341962', 'https://openalex.org/W2567527004', 'https://openalex.org/W2551467517', 'https://openalex.org/W2502897314', 'https://openalex.org/W2279998166', 'https://openalex.org/W2165171208', 'https://openalex.org/W2157514563', 'https://openalex.org/W2139596299', 'https://openalex.org/W2043297692', 'https://openalex.org/W2027413502', 'https://openalex.org/W2011211023', 'https://openalex.org/W2003126314', 'https://openalex.org/W1989978689', 'https://openalex.org/W1975473230', 'https://openalex.org/W1480791171'], 'abstract_inverted_index': {'OBJECTIVE:': [0], 'To': [1], 'observe': [2, 203], 'the': [3, 10, 16, 30, 40, 56, 63, 68, 73, 91, 118, 123, 135, 144, 171, 181, 204], 'effect': [4, 25, 145, 205], 'of': [5, 26, 29, 32, 39, 49, 51, 65, 70, 75, 88, 109, 120, 146, 149, 161, 164, 167, 184, 206], 'poly(ADP-ribose)': [6], 'polymerase(PARP)': [7], 'inhibitors': [8, 34, 79, 140, 158, 208], 'on': [9, 209], 'growth': [11, 147, 165], 'inhibition': [12, 28, 74, 148, 166, 211], 'by': [13, 45, 77, 82, 132, 212], 'cisplatin': [14, 71, 93, 101, 150, 168, 195], 'in': [15, 134, 151, 169, 218], 'Cis-sensitive': [17, 57, 172], 'and': [18, 37, 53, 58, 72, 98, 117, 128, 173], 'Cis-resistant': [19, 59, 174], 'lung': [20, 136, 153, 175, 219], 'cancer': [21, 137, 154, 176, 220], 'cell': [22, 60, 95, 103, 138, 155, 177, 190, 221], 'lines.METHODS:': [23], 'The': [24, 86], 'proliferation': [27, 210], 'combination': [31], 'PARP': [33, 78, 157, 207], 'with': [35, 62, 189], 'cispaltin': [36], 'that': [38, 180], 'single': [41], 'drugs': [42], 'were': [43, 80], 'detected': [44], 'MTT': [46], 'assay.The': [47], 'difference': [48], 'expression': [50, 87, 183], 'PARP-1': [52, 89, 185], 'PARP-2': [54], 'between': [55, 90], 'lines,together': [61], 'formation': [64, 119], 'Poly(ADP-ribose)(PAR)': [66], 'following': [67], 'exposure': [69, 108], 'PAR': [76, 121], 'analyzed': [81], 'western': [83], 'blot': [84], 'analysis.RESULTS:': [85], 'parent': [92], 'sensitive': [94, 193], 'lines': [96, 104, 191], 'PC9,PC14,SBC3': [97], 'their': [99], 'sub': [100], 'resistant': [102], 'was': [105, 114, 122], 'significantly': [106], 'different(P=0.028,0.013,0.008).After': [107], '60': [110], 'minutes': [111, 127], 'to': [112, 194, 202], 'cisplatin,PARP': [113], 'activated': [115], 'rapidly': [116], 'highest': [124], 'at': [125], '40': [126], 'could': [129], 'be': [130], 'inhibited': [131], 'DPQ': [133], 'lines(P0.05,t0).PARP': [139], 'did': [141], 'not': [142, 187], 'potentiate': [143], 'all': [152, 170], 'lines.CONCLUSIONS:': [156], 'brings': [159], 'effects': [160], 'no': [162], 'potentiation': [163], 'lines,which': [178], 'suggests': [179], 'different': [182], 'is': [186], 'related': [188], 'whether': [192], 'or': [196], 'not.Further': [197], 'investigations': [198], 'are': [199], 'still': [200], 'needed': [201], 'other': [213], 'DNA': [214], 'damage': [215], 'chemotherapy': [216], 'agents': [217], 'lines.': [222]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2349674900', 'counts_by_year': [], 'updated_date': '2024-12-08T17:30:58.663930', 'created_date': '2016-06-24'}