Title: Study on optimizing ethanol refluxing extraction for Xiaoqinglong patch by orthogonal design method
Abstract: OBJECTIVE To optimize the technological condition of ethanol refluxing extraction for Xiaoqinglong Patch.METHODS The content of ephedrinehydrochloride and Paeoniflorin extracted,which were regarded as the marker of detection,were determined by HPLC.On the basis of initial research,the general content data determined were used to optimize the refluxing extraction processing conditions by orthogonal test.RESULTS The optimum extraction condition was that the medicinal materials was extracted 3 time with 8-fold of 70 percent ethanol,2 hour for the first time and then 1 hour next two times.CONCLUSION The contents of Ephedrinehydrochloride and Paeoniflorin extracted by the optimum extraction process are high and the optimized process is stable and high efficient.
Publication Year: 2009
Publication Date: 2009-01-01
Language: en
Type: article
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