Title: Clinical observation of curative effect of carvedilol in patients with chronic heart failure
Abstract: Objective:To explore the efficacy and safety of carvedilol in patients with chronic heart failure.Methods:51cases of chronic heart failure were divided into two groups,namely carvedilol group(26cases)and control group(25cases).Their basic clinical characteristics were similar.LVEF and change of left ventricular diameter before and after6months of treatment were measured by color ultrasonographocardigram,and the alterations of NYHA cardiac function scale,blood pressure and heart rate were also observed simultaneously.Results:Compared with the control group after6months of treatment,LVEF of carveidilol group was significantly increased(46.52±6.24%vs39.62±5.63%,P0.05),both LVDd and LVDs were significantly shortened(LVDd:52.24±6.12mm vs58.34±6.31mm,LVDs:39.35±5.31mm vs43.71±5.64mm,all P0.05).The improvement of NYHA cardiac function scale in the carvedilol group after6months of treatment was superior to that in the control group.Conclusion:Patients with chronic heart failure treated with carvedilol is effective and safe.
Publication Year: 2005
Publication Date: 2005-01-01
Language: en
Type: article
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