Title: The Clinical Studies on the Safety and Efficacy of Glutathione for Injection for Patients with Chronic Viral and Toxic Hepatitis
Abstract: Aim To evaluate the clinical safety and efficacy of glutathione for injection for patients with chronic viral and toxic hepatitis.T5HZ]Methods The 122 patients with chronic viral and toxic hepatitis were selected and randomly divided into the treatment group and control group.In the treatment group,patients were intravenous injected with glutathione for injection 1 200mg qd;in the control group,patients were intravenous injected with potassium-magnesium aspartate 10ml×3 qd,for 4 weeks.Patients in the open group were administerd with the same drug as the treatment group.ResultsZAfter 4 weeks,in the treatment group,inappetence,debility,liver pain,windy and jaundice significantly decreased (P0.01).ALT from (485.91±442.65)U·L -1 decreased to (54.30±39.72)U·L -1(P0.01).AST from (262.95±288.71)U·L -1 decreased to (39.68±28.68)U·L -1(P0.01),the clinical efficacy was 86.89%.The control group(81.97%)resembled the treatment group in clinical efficacy(P0.05).Severe drug reactions of both groups were not discovered.Among the 103 Patients treated with glutathione the clinical efficacy was 92.23%.Conclusion This result suggests that glutathione for injection is a safe and effective treatment for chronic viral and toxic hepatitis.
Publication Year: 2006
Publication Date: 2006-01-01
Language: en
Type: article
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