Title: Antimicrobial activity of Gemini antimicrobial agents with different chemical structure
Abstract:To obtain strong activity antimicrobial agent,the antimicrobial properties of Gemini antimicrobial agents(C1,C2,C3 and C4) were evaluated by quantifying the minimal inhibitory concentration(MIC),n-dod...To obtain strong activity antimicrobial agent,the antimicrobial properties of Gemini antimicrobial agents(C1,C2,C3 and C4) were evaluated by quantifying the minimal inhibitory concentration(MIC),n-dodecyl-trimethylammonium bromide(DTAB) as a comparison.The results indicated that these Gemini antimicrobial agents against S.aurueus,E.coli and C.albicans were superior to DTAB.The MIC of C2 against S.aurueus and E.coli were 1.5 μg·L-1 and 3.91 μg·L-1,respectively.The MIC of C4 against C.albicans was 3.91 μg·L-1.these Gemini antimicrobial agents exhibited improved activity against a broad spectrum of Gram-positive and Gram-negative bacteria as well as yeast.Their antimicrobial properties rely on the Gemini molecular structures with longer length of main-chain,full-chain and R groups,their antimicrobial activities are stronger,and fluorinated alkyl groups can markedly improve their antimicrobial properties compared with the same hydrocarbon one.Read More
Publication Year: 2008
Publication Date: 2008-01-01
Language: en
Type: article
Access and Citation
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot