Title: Changes of post-operative cardiac injury markers and its clinical significance in beating heart direct version intracardiac surgery
Abstract: Objectives To investigate the changes of cardiac injury markers after beating heart direct version intracardiac surgery and its clinical significance. Methods 48 patients undergoing elective direct version intracardiac surgery(mitral valve replacement, MVR) were chosen. Changes of C-reaction protein(CRP),creation kinase MB isoform(CK-MB),cardiac troponin T (cTnT) and cardiac troponin I(cTnI) were detected at different time points. Electrocardiogram(UCG),hemodynamic parameters and clinical outcomes were recorded simultaneously. Results The cardiac injury markers were significantly elevated at the early time after the operation, reached the highest level at 12 hours postoperation. Among the 12 patients with abnormal cTnI at 48 hours after operation,2 died and 7 had severe post-operation adverse events. The rate of severe post-operation adverse events in patients with 12 hours post-operative cTnI over or below 10.00 μg/L were 66.7% and 12.1% respectively. Conclusions Early cardiac injury markers were elevated after direct version intracardiac surgery. Patients with elevated cardiac injury markers at 48 hours after operation or cTnI over 10.00 μg/L at 12 hours post-operation may indicate major post-operative adverse events.
Publication Year: 2003
Publication Date: 2003-01-01
Language: en
Type: article
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