Title: Differentiation of soft tissue lipoma from well-differentiated liposarcom on MRI
Abstract: Objective To evaluate the value of magnetic resonance imaging features in differentiating soft tissue lipoma from well-differentiated liposarcoma.Methods MR images of 30 patients with histologically verified fat-containing tumors(22 lipomas and 8 well-differentiated liposarcomas)were retrospectively reviewed.Well-differentiated liposarcomas and benign lipomas were compared in terms of the size of the lesion,percentage of adipose component,number of thick septa,nodular and(or)patchy nonadipose component,contrast enhancement patterns and the margin characters of the lesion.Results The mean size of lipomas[(64±35)mm]was significantly smaller(t=4.263,P0.01)than that of well- differentiated liposarcomas[(138±44)mm],and the mean percentage of adipose component of lipomas [(94±6)%]was significantly larger(t=5.903,P0.01)than that of well-differentiated liposarcomas [(74±9)%].Thelipomas with more than two thick septa(3/22)were significantly less(P0.01)than well-differentiated liposarcomas with(8/8),and lopomas with nodular and/ or patchy nonadipose components(4/22)were significantly less(P0.01)than well-differentiated liposarcomas with(8/8).The degree of contrast enhancement in 15 lipomas(4/15 mild to moderate enhancement)was significantly lower (P0.01)than that in well-differentiated liposarcomas(1/8 moderate and 7/8 strong enhancement). Conclusion MRI is helpful in distinguishing soft tissue lipoma and well-differentiated liposarcoma. Compared with lipoma,features that suggest well-differentiated liposarcoma include large lesion size, decreased percentage of fat composition,presence of more than two thick septa,presence of nodular and/or patchy nonadipose areas and strong enhancement.
Publication Year: 2007
Publication Date: 2007-01-01
Language: en
Type: article
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