Title: The Effect of General Anesthesia Combined with Epidural Anesthesia for Earlier Period POCD in OlderMale Patients
Abstract: Objective To observe the effect of general anesthesia combined with epidural anesthesia for earlier period postoperation cognitive dysfunction( POCD)in older male patients. Methods 60 ASA I.Ⅱ male thoracic surgery patients aged 60.75 years under general anesthesia were enrolled in this study. Body weight were normal. The patients were randomly assigned to two study groups:group A received general anesthesia combined with epidural anesthesia,group B received general anesthesia.Anesthesia was induced with midazolam,sufentanyl,rocuronium,propofol,and maintained with inhalate sevoflurane and intravenous propofol. The MMSE scores were observed for the preoperative and postoperative 3 h. Results The incidences of POCD were 31% and 29% for older male patients among group A and B,there is difference of statistics for the MMSE scores between the preoperative and postoperative(P 0.05). There is no difference with the postoperative between two groups(P 0.05). Conclusion General anesthesia combined with epidural anesthesia was to utilized safely for oldermale patients that it did not raise the risk of earlier period POCD.
Publication Year: 2014
Publication Date: 2014-01-01
Language: en
Type: article
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