Title: [Improvements of lentiviral vector and its application in gene therapy of hematological diseases].
Abstract: As lentiviral vector holds the characteristics of higher transfection to non-dividing cells, larger capacity of transfer gene fragments, long-term expression of therapeutic gene and lower rate of immunological response, therefore it becomes potential viral vector in gene therapy. Improvements of lentiviral vector, human immunodeficiency virus type-I as example, and its application in gene transfer for gene therapy of hematological diseases are emphasized in this review.
Publication Year: 2003
Publication Date: 2003-04-01
Language: en
Type: article
Indexed In: ['pubmed']
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