Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2346260187', 'doi': 'https://doi.org/10.1002/pd.4837', 'title': 'Noninvasive prenatal testing (NIPT) in twin pregnancies with treatment of assisted reproductive techniques (ART) in a single center', 'display_name': 'Noninvasive prenatal testing (NIPT) in twin pregnancies with treatment of assisted reproductive techniques (ART) in a single center', 'publication_year': 2016, 'publication_date': '2016-05-06', 'ids': {'openalex': 'https://openalex.org/W2346260187', 'doi': 'https://doi.org/10.1002/pd.4837', 'mag': '2346260187', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/27150972'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/pd.4837', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S171405753', 'display_name': 'Prenatal Diagnosis', 'issn_l': '0197-3851', 'issn': ['0197-3851', '1097-0223'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5004909924', 'display_name': 'Yue‐Qiu Tan', 'orcid': 'https://orcid.org/0000-0002-8359-4654'}, 'institutions': [{'id': 'https://openalex.org/I4210119845', 'display_name': 'National Engineering Research Center of Human Stem Cells', 'ror': 'https://ror.org/02khfyc93', 'country_code': 'CN', 'type': 'facility', 'lineage': ['https://openalex.org/I4210119845']}, {'id': 'https://openalex.org/I139660479', 'display_name': 'Central South University', 'ror': 'https://ror.org/00f1zfq44', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I139660479']}, {'id': 'https://openalex.org/I4210102182', 'display_name': 'Reproductive & Genetic Hospital CITIC-Xiangya', 'ror': 'https://ror.org/01ar3e651', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210102182']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yueqiu Tan', 'raw_affiliation_strings': ['Institute of Reproductive and Stem Cell Engineering, Central South University, Changsha, China', 'Key Laboratory of Reproductive and Stem Cell Engineering, Ministry of Health, Changsha, China', 'Reproductive and Genetic Hospital of CITIC-Xiangya, Changsha, China'], 'affiliations': [{'raw_affiliation_string': 'Institute of Reproductive and Stem Cell Engineering, Central South University, Changsha, China', 'institution_ids': ['https://openalex.org/I4210119845', 'https://openalex.org/I139660479']}, {'raw_affiliation_string': 'Key Laboratory of Reproductive and Stem Cell Engineering, Ministry of Health, Changsha, China', 'institution_ids': ['https://openalex.org/I4210119845']}, {'raw_affiliation_string': 'Reproductive and Genetic Hospital of CITIC-Xiangya, Changsha, China', 'institution_ids': ['https://openalex.org/I4210102182']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5001596478', 'display_name': 'Ya Gao', 'orcid': 'https://orcid.org/0000-0002-5094-9842'}, 'institutions': [{'id': 'https://openalex.org/I4210149137', 'display_name': 'China National GeneBank', 'ror': 'https://ror.org/03n9hr695', 'country_code': 'CN', 'type': 'archive', 'lineage': ['https://openalex.org/I4210149137']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Ya Gao', 'raw_affiliation_strings': ['China National Genebank-Shenzhen, BGI-Shenzhen, Shenzhen, China', 'China National Genebank‐Shenzhen BGI‐Shenzhen Shenzhen China'], 'affiliations': [{'raw_affiliation_string': 'China National Genebank-Shenzhen, BGI-Shenzhen, Shenzhen, China', 'institution_ids': ['https://openalex.org/I4210149137']}, {'raw_affiliation_string': 'China National Genebank‐Shenzhen BGI‐Shenzhen Shenzhen China', 'institution_ids': ['https://openalex.org/I4210149137']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5080552339', 'display_name': 'Ge Lin', 'orcid': 'https://orcid.org/0000-0002-3877-2546'}, 'institutions': [{'id': 'https://openalex.org/I4210119845', 'display_name': 'National Engineering Research Center of Human Stem Cells', 'ror': 'https://ror.org/02khfyc93', 'country_code': 'CN', 'type': 'facility', 'lineage': ['https://openalex.org/I4210119845']}, {'id': 'https://openalex.org/I139660479', 'display_name': 'Central South University', 'ror': 'https://ror.org/00f1zfq44', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I139660479']}, {'id': 'https://openalex.org/I4210102182', 'display_name': 'Reproductive & Genetic Hospital CITIC-Xiangya', 'ror': 'https://ror.org/01ar3e651', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210102182']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Ge Lin', 'raw_affiliation_strings': ['Institute of Reproductive and Stem Cell Engineering, Central South University, Changsha, China', 'Key Laboratory of Reproductive and Stem Cell Engineering, Ministry of Health, Changsha, China', 'Reproductive and Genetic Hospital of CITIC-Xiangya, Changsha, China'], 'affiliations': [{'raw_affiliation_string': 'Institute of Reproductive and Stem Cell Engineering, Central South University, Changsha, China', 'institution_ids': ['https://openalex.org/I4210119845', 'https://openalex.org/I139660479']}, {'raw_affiliation_string': 'Key Laboratory of Reproductive and Stem Cell Engineering, Ministry of Health, Changsha, China', 'institution_ids': ['https://openalex.org/I4210119845']}, {'raw_affiliation_string': 'Reproductive and Genetic Hospital of CITIC-Xiangya, Changsha, China', 'institution_ids': ['https://openalex.org/I4210102182']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5005087952', 'display_name': 'Meili Fu', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I100135526', 'display_name': 'BGI Group (China)', 'ror': 'https://ror.org/045pn2j94', 'country_code': 'CN', 'type': 'company', 'lineage': ['https://openalex.org/I100135526']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Meili Fu', 'raw_affiliation_strings': ['Clinical laboratory of BGI Health, BGI-Shenzhen, Shenzhen, China'], 'affiliations': [{'raw_affiliation_string': 'Clinical laboratory of BGI Health, BGI-Shenzhen, Shenzhen, China', 'institution_ids': ['https://openalex.org/I100135526']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100707228', 'display_name': 'Xihong Li', 'orcid': 'https://orcid.org/0000-0002-0986-760X'}, 'institutions': [{'id': 'https://openalex.org/I4210102182', 'display_name': 'Reproductive & Genetic Hospital CITIC-Xiangya', 'ror': 'https://ror.org/01ar3e651', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210102182']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Xihong Li', 'raw_affiliation_strings': ['Reproductive and Genetic Hospital of CITIC-Xiangya, Changsha, China'], 'affiliations': [{'raw_affiliation_string': 'Reproductive and Genetic Hospital of CITIC-Xiangya, Changsha, China', 'institution_ids': ['https://openalex.org/I4210102182']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5108969653', 'display_name': 'Xuyang Yin', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210149137', 'display_name': 'China National GeneBank', 'ror': 'https://ror.org/03n9hr695', 'country_code': 'CN', 'type': 'archive', 'lineage': ['https://openalex.org/I4210149137']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Xuyang Yin', 'raw_affiliation_strings': ['China National Genebank-Shenzhen, BGI-Shenzhen, Shenzhen, China', 'China National Genebank‐Shenzhen BGI‐Shenzhen Shenzhen China'], 'affiliations': [{'raw_affiliation_string': 'China National Genebank-Shenzhen, BGI-Shenzhen, Shenzhen, China', 'institution_ids': ['https://openalex.org/I4210149137']}, {'raw_affiliation_string': 'China National Genebank‐Shenzhen BGI‐Shenzhen Shenzhen China', 'institution_ids': ['https://openalex.org/I4210149137']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5074544812', 'display_name': 'Juan Du', 'orcid': 'https://orcid.org/0000-0002-5701-6703'}, 'institutions': [{'id': 'https://openalex.org/I4210102182', 'display_name': 'Reproductive & Genetic Hospital CITIC-Xiangya', 'ror': 'https://ror.org/01ar3e651', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210102182']}, {'id': 'https://openalex.org/I4210119845', 'display_name': 'National Engineering Research Center of Human Stem Cells', 'ror': 'https://ror.org/02khfyc93', 'country_code': 'CN', 'type': 'facility', 'lineage': ['https://openalex.org/I4210119845']}, {'id': 'https://openalex.org/I139660479', 'display_name': 'Central South University', 'ror': 'https://ror.org/00f1zfq44', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I139660479']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Juan Du', 'raw_affiliation_strings': ['Institute of Reproductive and Stem Cell Engineering, Central South University, Changsha, China', 'Key Laboratory of Reproductive and Stem Cell Engineering, Ministry of Health, Changsha, China', 'Reproductive and Genetic Hospital of CITIC-Xiangya, Changsha, China'], 'affiliations': [{'raw_affiliation_string': 'Reproductive and Genetic Hospital of CITIC-Xiangya, Changsha, China', 'institution_ids': ['https://openalex.org/I4210102182']}, {'raw_affiliation_string': 'Institute of Reproductive and Stem Cell Engineering, Central South University, Changsha, China', 'institution_ids': ['https://openalex.org/I4210119845', 'https://openalex.org/I139660479']}, {'raw_affiliation_string': 'Key Laboratory of Reproductive and Stem Cell Engineering, Ministry of Health, Changsha, China', 'institution_ids': ['https://openalex.org/I4210119845']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100337152', 'display_name': 'Jing Li', 'orcid': 'https://orcid.org/0009-0007-3236-9637'}, 'institutions': [], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Jing Li', 'raw_affiliation_strings': ['Clinical Laboratory of BGI Health, BGI-Wuhan, Wuhan, China'], 'affiliations': [{'raw_affiliation_string': 'Clinical Laboratory of BGI Health, BGI-Wuhan, Wuhan, China', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100320344', 'display_name': 'Wen Li', 'orcid': 'https://orcid.org/0000-0003-2360-9831'}, 'institutions': [{'id': 'https://openalex.org/I4210102182', 'display_name': 'Reproductive & Genetic Hospital CITIC-Xiangya', 'ror': 'https://ror.org/01ar3e651', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210102182']}, {'id': 'https://openalex.org/I4210119845', 'display_name': 'National Engineering Research Center of Human Stem Cells', 'ror': 'https://ror.org/02khfyc93', 'country_code': 'CN', 'type': 'facility', 'lineage': ['https://openalex.org/I4210119845']}, {'id': 'https://openalex.org/I139660479', 'display_name': 'Central South University', 'ror': 'https://ror.org/00f1zfq44', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I139660479']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Wen Li', 'raw_affiliation_strings': ['Institute of Reproductive and Stem Cell Engineering, Central South University, Changsha, China', 'Key Laboratory of Reproductive and Stem Cell Engineering, Ministry of Health, Changsha, China', 'Reproductive and Genetic Hospital of CITIC-Xiangya, Changsha, China'], 'affiliations': [{'raw_affiliation_string': 'Reproductive and Genetic Hospital of CITIC-Xiangya, Changsha, China', 'institution_ids': ['https://openalex.org/I4210102182']}, {'raw_affiliation_string': 'Key Laboratory of Reproductive and Stem Cell Engineering, Ministry of Health, Changsha, China', 'institution_ids': ['https://openalex.org/I4210119845']}, {'raw_affiliation_string': 'Institute of Reproductive and Stem Cell Engineering, Central South University, Changsha, China', 'institution_ids': ['https://openalex.org/I4210119845', 'https://openalex.org/I139660479']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5058866104', 'display_name': 'Huanhuan Peng', 'orcid': 'https://orcid.org/0000-0002-4515-6979'}, 'institutions': [], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Huanhuan Peng', 'raw_affiliation_strings': ['Clinical Laboratory of BGI Health, BGI-Wuhan, Wuhan, China'], 'affiliations': [{'raw_affiliation_string': 'Clinical Laboratory of BGI Health, BGI-Wuhan, Wuhan, China', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5073618545', 'display_name': 'Yuying Yuan', 'orcid': 'https://orcid.org/0000-0001-6322-7550'}, 'institutions': [{'id': 'https://openalex.org/I100135526', 'display_name': 'BGI Group (China)', 'ror': 'https://ror.org/045pn2j94', 'country_code': 'CN', 'type': 'company', 'lineage': ['https://openalex.org/I100135526']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yuying Yuan', 'raw_affiliation_strings': ['Clinical laboratory of BGI Health, BGI-Shenzhen, Shenzhen, China'], 'affiliations': [{'raw_affiliation_string': 'Clinical laboratory of BGI Health, BGI-Shenzhen, Shenzhen, China', 'institution_ids': ['https://openalex.org/I100135526']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100400043', 'display_name': 'Fang Chen', 'orcid': 'https://orcid.org/0000-0003-4971-8729'}, 'institutions': [{'id': 'https://openalex.org/I124055696', 'display_name': 'University of Copenhagen', 'ror': 'https://ror.org/035b05819', 'country_code': 'DK', 'type': 'education', 'lineage': ['https://openalex.org/I124055696']}, {'id': 'https://openalex.org/I4210149137', 'display_name': 'China National GeneBank', 'ror': 'https://ror.org/03n9hr695', 'country_code': 'CN', 'type': 'archive', 'lineage': ['https://openalex.org/I4210149137']}], 'countries': ['CN', 'DK'], 'is_corresponding': False, 'raw_author_name': 'Fang Chen', 'raw_affiliation_strings': ['China National Genebank-Shenzhen, BGI-Shenzhen, Shenzhen, China', 'China National Genebank‐Shenzhen BGI‐Shenzhen Shenzhen China', 'Section of Molecular Disease Biology, Department of Veterinary Disease Biology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark'], 'affiliations': [{'raw_affiliation_string': 'Section of Molecular Disease Biology, Department of Veterinary Disease Biology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark', 'institution_ids': ['https://openalex.org/I124055696']}, {'raw_affiliation_string': 'China National Genebank-Shenzhen, BGI-Shenzhen, Shenzhen, China', 'institution_ids': ['https://openalex.org/I4210149137']}, {'raw_affiliation_string': 'China National Genebank‐Shenzhen BGI‐Shenzhen Shenzhen China', 'institution_ids': ['https://openalex.org/I4210149137']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5110203711', 'display_name': 'Fuman Jiang', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I100135526', 'display_name': 'BGI Group (China)', 'ror': 'https://ror.org/045pn2j94', 'country_code': 'CN', 'type': 'company', 'lineage': ['https://openalex.org/I100135526']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Fuman Jiang', 'raw_affiliation_strings': ['Clinical laboratory of BGI Health, BGI-Shenzhen, Shenzhen, China'], 'affiliations': [{'raw_affiliation_string': 'Clinical laboratory of BGI Health, BGI-Shenzhen, Shenzhen, China', 'institution_ids': ['https://openalex.org/I100135526']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5110715690', 'display_name': 'Hongyun Zhang', 'orcid': 'https://orcid.org/0000-0003-3014-1878'}, 'institutions': [{'id': 'https://openalex.org/I100135526', 'display_name': 'BGI Group (China)', 'ror': 'https://ror.org/045pn2j94', 'country_code': 'CN', 'type': 'company', 'lineage': ['https://openalex.org/I100135526']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Hongyun Zhang', 'raw_affiliation_strings': ['Clinical laboratory of BGI Health, BGI-Shenzhen, Shenzhen, China'], 'affiliations': [{'raw_affiliation_string': 'Clinical laboratory of BGI Health, BGI-Shenzhen, Shenzhen, China', 'institution_ids': ['https://openalex.org/I100135526']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5109313200', 'display_name': 'Guangxiu Lu', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210119845', 'display_name': 'National Engineering Research Center of Human Stem Cells', 'ror': 'https://ror.org/02khfyc93', 'country_code': 'CN', 'type': 'facility', 'lineage': ['https://openalex.org/I4210119845']}, {'id': 'https://openalex.org/I4210102182', 'display_name': 'Reproductive & Genetic Hospital CITIC-Xiangya', 'ror': 'https://ror.org/01ar3e651', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210102182']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Guangxiu Lu', 'raw_affiliation_strings': ['Key Laboratory of Reproductive and Stem Cell Engineering, Ministry of Health, Changsha, China', 'Reproductive and Genetic Hospital of CITIC-Xiangya, Changsha, China'], 'affiliations': [{'raw_affiliation_string': 'Key Laboratory of Reproductive and Stem Cell Engineering, Ministry of Health, Changsha, China', 'institution_ids': ['https://openalex.org/I4210119845']}, {'raw_affiliation_string': 'Reproductive and Genetic Hospital of CITIC-Xiangya, Changsha, China', 'institution_ids': ['https://openalex.org/I4210102182']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5102953181', 'display_name': 'Fei Gong', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210119845', 'display_name': 'National Engineering Research Center of Human Stem Cells', 'ror': 'https://ror.org/02khfyc93', 'country_code': 'CN', 'type': 'facility', 'lineage': ['https://openalex.org/I4210119845']}, {'id': 'https://openalex.org/I139660479', 'display_name': 'Central South University', 'ror': 'https://ror.org/00f1zfq44', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I139660479']}, {'id': 'https://openalex.org/I4210102182', 'display_name': 'Reproductive & Genetic Hospital CITIC-Xiangya', 'ror': 'https://ror.org/01ar3e651', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210102182']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Fei Gong', 'raw_affiliation_strings': ['Institute of Reproductive and Stem Cell Engineering, Central South University, Changsha, China', 'Key Laboratory of Reproductive and Stem Cell Engineering, Ministry of Health, Changsha, China', 'Reproductive and Genetic Hospital of CITIC-Xiangya, Changsha, China'], 'affiliations': [{'raw_affiliation_string': 'Institute of Reproductive and Stem Cell Engineering, Central South University, Changsha, China', 'institution_ids': ['https://openalex.org/I4210119845', 'https://openalex.org/I139660479']}, {'raw_affiliation_string': 'Key Laboratory of Reproductive and Stem Cell Engineering, Ministry of Health, Changsha, China', 'institution_ids': ['https://openalex.org/I4210119845']}, {'raw_affiliation_string': 'Reproductive and Genetic Hospital of CITIC-Xiangya, Changsha, China', 'institution_ids': ['https://openalex.org/I4210102182']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5100391970', 'display_name': 'Wei Wang', 'orcid': 'https://orcid.org/0000-0002-4381-5686'}, 'institutions': [{'id': 'https://openalex.org/I100135526', 'display_name': 'BGI Group (China)', 'ror': 'https://ror.org/045pn2j94', 'country_code': 'CN', 'type': 'company', 'lineage': ['https://openalex.org/I100135526']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Wei Wang', 'raw_affiliation_strings': ['BGI-Shenzhen, Shenzhen, China', 'Clinical laboratory of BGI Health, BGI-Shenzhen, Shenzhen, China'], 'affiliations': [{'raw_affiliation_string': 'Clinical laboratory of BGI Health, BGI-Shenzhen, Shenzhen, China', 'institution_ids': ['https://openalex.org/I100135526']}, {'raw_affiliation_string': 'BGI-Shenzhen, Shenzhen, China', 'institution_ids': ['https://openalex.org/I100135526']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 6, 'corresponding_author_ids': ['https://openalex.org/A5102953181', 'https://openalex.org/A5100391970'], 'corresponding_institution_ids': ['https://openalex.org/I4210119845', 'https://openalex.org/I139660479', 'https://openalex.org/I4210102182', 'https://openalex.org/I100135526'], 'apc_list': {'value': 4640, 'currency': 'USD', 'value_usd': 4640, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 10.752, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 55, 'citation_normalized_percentile': {'value': 0.999944, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 96, 'max': 97}, 'biblio': {'volume': '36', 'issue': '7', 'first_page': '672', 'last_page': '679'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10978', 'display_name': 'Prenatal Screening and Diagnostics', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2735', 'display_name': 'Pediatrics, Perinatology and Child Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10978', 'display_name': 'Prenatal Screening and Diagnostics', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2735', 'display_name': 'Pediatrics, Perinatology and Child Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11732', 'display_name': 'Assisted Reproductive Technology and Twin Pregnancy', 'score': 0.9949, 'subfield': {'id': 'https://openalex.org/subfields/2735', 'display_name': 'Pediatrics, Perinatology and Child Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/trisomy', 'display_name': 'Trisomy', 'score': 0.6597837}, {'id': 'https://openalex.org/keywords/twin-pregnancy', 'display_name': 'Twin Pregnancy', 'score': 0.5836442}, {'id': 'https://openalex.org/keywords/assisted-reproductive-technology', 'display_name': 'Assisted Reproductive Technology', 'score': 0.50377077}, {'id': 'https://openalex.org/keywords/false-positive-rate', 'display_name': 'False positive rate', 'score': 0.43776762}], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.7056608}, {'id': 'https://openalex.org/C131872663', 'wikidata': 'https://www.wikidata.org/wiki/Q5284418', 'display_name': 'Obstetrics', 'level': 1, 'score': 0.66241205}, {'id': 'https://openalex.org/C2776229224', 'wikidata': 'https://www.wikidata.org/wiki/Q844903', 'display_name': 'Trisomy', 'level': 2, 'score': 0.6597837}, {'id': 'https://openalex.org/C29456083', 'wikidata': 'https://www.wikidata.org/wiki/Q1221899', 'display_name': 'Gynecology', 'level': 1, 'score': 0.59114873}, {'id': 'https://openalex.org/C2909855057', 'wikidata': 'https://www.wikidata.org/wiki/Q159979', 'display_name': 'Twin Pregnancy', 'level': 4, 'score': 0.5836442}, {'id': 'https://openalex.org/C2778258057', 'wikidata': 'https://www.wikidata.org/wiki/Q1136569', 'display_name': 'Prenatal diagnosis', 'level': 4, 'score': 0.5115908}, {'id': 'https://openalex.org/C2779234561', 'wikidata': 'https://www.wikidata.org/wiki/Q11995', 'display_name': 'Pregnancy', 'level': 2, 'score': 0.50756586}, {'id': 'https://openalex.org/C3019719930', 'wikidata': 'https://www.wikidata.org/wiki/Q3910099', 'display_name': 'Predictive value', 'level': 2, 'score': 0.5058932}, {'id': 'https://openalex.org/C500014431', 'wikidata': 'https://www.wikidata.org/wiki/Q25862', 'display_name': 'Assisted reproductive technology', 'level': 4, 'score': 0.50377077}, {'id': 'https://openalex.org/C95922358', 'wikidata': 'https://www.wikidata.org/wiki/Q5432725', 'display_name': 'False positive rate', 'level': 2, 'score': 0.43776762}, {'id': 'https://openalex.org/C46973012', 'wikidata': 'https://www.wikidata.org/wiki/Q28627', 'display_name': 'Gestation', 'level': 3, 'score': 0.25530618}, {'id': 'https://openalex.org/C172680121', 'wikidata': 'https://www.wikidata.org/wiki/Q26513', 'display_name': 'Fetus', 'level': 3, 'score': 0.2527607}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.111601144}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.08969274}, {'id': 'https://openalex.org/C2777688143', 'wikidata': 'https://www.wikidata.org/wiki/Q179399', 'display_name': 'Infertility', 'level': 3, 'score': 0.08303252}, {'id': 'https://openalex.org/C105795698', 'wikidata': 'https://www.wikidata.org/wiki/Q12483', 'display_name': 'Statistics', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C33923547', 'wikidata': 'https://www.wikidata.org/wiki/Q395', 'display_name': 'Mathematics', 'level': 0, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D025063', 'descriptor_name': 'Chromosome Disorders', 'qualifier_ui': 'Q000175', 'qualifier_name': 'diagnosis', 'is_major_topic': True}, {'descriptor_ui': 'D004247', 'descriptor_name': 'DNA', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': True}, {'descriptor_ui': 'D059285', 'descriptor_name': 'Pregnancy, Twin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D027724', 'descriptor_name': 'Reproductive Techniques, Assisted', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D017422', 'descriptor_name': 'Sequence Analysis, DNA', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': True}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002681', 'descriptor_name': 'China', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D025063', 'descriptor_name': 'Chromosome Disorders', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D025063', 'descriptor_name': 'Chromosome Disorders', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D002882', 'descriptor_name': 'Chromosomes, Human, Pair 13', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002882', 'descriptor_name': 'Chromosomes, Human, Pair 13', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D002887', 'descriptor_name': 'Chromosomes, Human, Pair 18', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002887', 'descriptor_name': 'Chromosomes, Human, Pair 18', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D004247', 'descriptor_name': 'DNA', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004247', 'descriptor_name': 'DNA', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D004314', 'descriptor_name': 'Down Syndrome', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004314', 'descriptor_name': 'Down Syndrome', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D004314', 'descriptor_name': 'Down Syndrome', 'qualifier_ui': 'Q000175', 'qualifier_name': 'diagnosis', 'is_major_topic': False}, {'descriptor_ui': 'D004624', 'descriptor_name': 'Embryo Transfer', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005307', 'descriptor_name': 'Fertilization in Vitro', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007621', 'descriptor_name': 'Karyotyping', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011237', 'descriptor_name': 'Predictive Value of Tests', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011247', 'descriptor_name': 'Pregnancy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011446', 'descriptor_name': 'Prospective Studies', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017422', 'descriptor_name': 'Sequence Analysis, DNA', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020554', 'descriptor_name': 'Sperm Injections, Intracytoplasmic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014314', 'descriptor_name': 'Trisomy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014314', 'descriptor_name': 'Trisomy', 'qualifier_ui': 'Q000175', 'qualifier_name': 'diagnosis', 'is_major_topic': False}, {'descriptor_ui': 'D014314', 'descriptor_name': 'Trisomy', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D000073839', 'descriptor_name': 'Trisomy 13 Syndrome', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000073842', 'descriptor_name': 'Trisomy 18 Syndrome', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D055815', 'descriptor_name': 'Young Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/pd.4837', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S171405753', 'display_name': 'Prenatal Diagnosis', 'issn_l': '0197-3851', 'issn': ['0197-3851', '1097-0223'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/27150972', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.8}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 49, 'referenced_works': ['https://openalex.org/W1577578665', 'https://openalex.org/W1583962399', 'https://openalex.org/W1700022468', 'https://openalex.org/W1972431488', 'https://openalex.org/W1972929336', 'https://openalex.org/W1975897221', 'https://openalex.org/W1978021217', 'https://openalex.org/W1987256536', 'https://openalex.org/W1991732049', 'https://openalex.org/W2002869944', 'https://openalex.org/W2005652149', 'https://openalex.org/W2007776605', 'https://openalex.org/W2009594120', 'https://openalex.org/W2015093746', 'https://openalex.org/W2018169421', 'https://openalex.org/W2023879574', 'https://openalex.org/W2049706382', 'https://openalex.org/W2054150163', 'https://openalex.org/W2063703489', 'https://openalex.org/W2064609638', 'https://openalex.org/W2067599274', 'https://openalex.org/W2070930343', 'https://openalex.org/W2081483776', 'https://openalex.org/W2087184623', 'https://openalex.org/W2099650901', 'https://openalex.org/W2106598824', 'https://openalex.org/W2107242272', 'https://openalex.org/W2108641027', 'https://openalex.org/W2110983499', 'https://openalex.org/W2112201740', 'https://openalex.org/W2118209929', 'https://openalex.org/W2122153888', 'https://openalex.org/W2124145958', 'https://openalex.org/W2131313813', 'https://openalex.org/W2133747855', 'https://openalex.org/W2134744749', 'https://openalex.org/W2139926668', 'https://openalex.org/W2144067971', 'https://openalex.org/W2155606271', 'https://openalex.org/W2156450635', 'https://openalex.org/W2156496744', 'https://openalex.org/W2166679178', 'https://openalex.org/W2167181759', 'https://openalex.org/W2168219608', 'https://openalex.org/W2169514348', 'https://openalex.org/W2172268977', 'https://openalex.org/W2740669386', 'https://openalex.org/W3110803468', 'https://openalex.org/W906205929'], 'related_works': ['https://openalex.org/W4239116640', 'https://openalex.org/W4231091002', 'https://openalex.org/W3124973648', 'https://openalex.org/W2122583087', 'https://openalex.org/W2070129217', 'https://openalex.org/W2062286717', 'https://openalex.org/W2017104886', 'https://openalex.org/W1990268980', 'https://openalex.org/W1979077699', 'https://openalex.org/W1969022859'], 'abstract_inverted_index': {'Abstract': [0], 'Objective': [1], 'The': [2, 159], 'objective': [3], 'of': [4, 12, 23, 93, 101, 106, 138, 153, 156, 196], 'the': [5, 10, 21, 154, 186, 201], 'study': [6], 'is': [7], 'to': [8, 188], 'report': [9], 'performance': [11], 'noninvasive': [13], 'prenatal': [14, 198], 'testing': [15], '(NIPT)': [16], 'in': [17, 60, 117, 204], 'twin': [18, 38, 206], 'pregnancies': [19, 39], 'after': [20, 75], 'treatment': [22], 'assisted': [24], 'reproductive': [25], 'technology': [26], '(ART).': [27], 'Method': [28], 'In': [29, 91], 'two': [30], 'years': [31], 'period,': [32], '565': [33, 94], 'pregnant': [34, 147], 'women': [35], 'with': [36, 127, 149], 'ART': [37, 205], 'were': [40, 66, 73, 108, 134], 'prospectively': [41], 'tested': [42], 'by': [43, 56, 68, 110, 114, 136], 'NIPT': [44, 64, 81, 96, 111, 128, 184], 'for': [45, 47], 'screening': [46, 199], 'trisomy': [48], '21': [49], '(T21),': [50], '18': [51], '(T18),': [52], 'and': [53, 82, 112, 179], '13': [54], '(T13)': [55], 'sequencing': [57], 'cell‐free': [58], 'DNA': [59], 'maternal': [61], 'plasma.': [62], 'Positive': [63], 'results': [65, 72, 84], 'confirmed': [67, 113, 135], 'karyotyping,': [69, 115], 'while': [70, 141], 'negative': [71, 129, 168], 'interviewed': [74], 'delivery.': [76], 'Pregnant': [77], 'decision': [78], 'based': [79], 'on': [80], 'confirmation': [83], 'was': [85, 170], 'discussed': [86], 'during': [87], 'post‐test': [88], 'counseling.': [89], 'Results': [90], 'total': [92], 'cases,': [95], 'had': [97, 145], 'a': [98, 192], 'failure': [99], 'rate': [100], '0.9%': [102], '(5/565).': [103], 'Four': [104], 'cases': [105, 126, 132, 143, 162], 'T21': [107], 'identified': [109], 'resulting': [116], '100%': [118], '(95%CI': [119], '39.8%–100%)': [120], 'positive': [121, 176, 182], 'predictive': [122, 177], 'value.': [123], 'Among': [124], '556': [125], 'results,': [130], '506': [131], '(91.0%)': [133], 'follow‐up': [137], 'postnatal': [139], 'phenotypes,': [140], '33': [142], '(5.9%)': [144], 'adverse': [146], 'outcomes': [148], 'unconfirmed': [150], 'reasons': [151], 'because': [152], 'lack': [155], 'cytogenetic': [157], 'samples.': [158], 'remaining': [160], '17': [161], '(3.1%)': [163], 'refused': [164], 'follow‐up.': [165], 'No': [166], 'false': [167, 181], 'result': [169], 'reported.': [171], 'Conclusion': [172], 'With': [173], 'apparently': [174], 'high': [175], 'value': [178], 'low': [180], 'rate,': [183], 'has': [185], 'potential': [187], 'be': [189], 'used': [190], 'as': [191], 'good': [193], 'alternative': [194], 'approach': [195], 'conventional': [197], 'at': [200], 'first': [202], 'trimester': [203], 'pregnancy.': [207], '©': [208], '2016': [209], 'John': [210], 'Wiley': [211], '&': [212], 'Sons,': [213], 'Ltd.': [214]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2346260187', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 5}, {'year': 2022, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 8}, {'year': 2020, 'cited_by_count': 9}, {'year': 2019, 'cited_by_count': 8}, {'year': 2018, 'cited_by_count': 14}, {'year': 2017, 'cited_by_count': 5}, {'year': 2016, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 1}], 'updated_date': '2024-12-24T12:40:57.317238', 'created_date': '2016-06-24'}