Title: Perioperative Stress Cardiomyopathy in Simultaneous Liver and Kidney Transplantation: A Call for Early Consideration of Mechanical Circulatory Support
Abstract: STRESS (TAKOTSUBO) CARDIOMYOPATHY is a relatively novel form of acute myocardial dysfunction. Initially described 25 years ago, it has been studied extensively, and an International Takotsubo Registry (http://www.takotsubo-registry.com/), a consortium of 26 centers, was established in 2011 in Zurich, Switzerland “to find the pathophysiology, epidemiologic features and clinical course of this important disease.” Nevertheless, awareness of the gravity of the clinical presentation of perioperative stress cardiomyopathy is lacking, possibly due to a call for a temporary ban on case report publication on the topic. 1 London M.J. Perioperative stress cardiomyopathy: Case reports matter. A A Case Rep. 2016; 6: 1-2 Crossref PubMed Scopus (1) Google Scholar Particularly puzzling is the paucity of case reports of stress cardiomyopathy in liver transplantation settings, 2 Lee H.R. Hurst R.T. Vargas H.E. Transient left ventricular apical ballooning syndrome (Takotsubo cardiomyopathy) following orthotopic liver transplantation. Liver Transpl. 2007; 13: 1343-1345 Crossref PubMed Scopus (25) Google Scholar , 3 Tiwari A.K. D’Attellis N. Intraoperative left ventricular apical ballooning: Transient Takotsubo cardiomyopathy during orthotopic liver transplantation. J Cardiothorac Vasc Anesth. 2008; 22: 442-445 Abstract Full Text Full Text PDF PubMed Scopus (33) Google Scholar , 4 Eagle S.S. Thompson A. Fong P.P. et al. Takotsubo cardiomyopathy and coronary vasospasm during orthotopic liver transplantation: Separate entities or common mechanism?. J Cardiothorac Vasc Anesth. 2010; 24: 629-632 Abstract Full Text Full Text PDF PubMed Scopus (26) Google Scholar , 5 Tachotti Pires LJ, Cardoso Curiati MN, Vissoci Reiche F, et al: Stress-induced cardiomyopathy (Takotsubo cardiomyopathy) after liver transplantation–report of two cases. Transplant Proc 44(8)2497-2500, 3012 Google Scholar , 6 Bedanova H. Orban M. Nemec P. Postoperative left ventricular apical ballooning: Transient Takotsubo cardiomyopathy following orthotopic liver transplantation. Am J Case Rep. 2013; 14: 494-497 Crossref PubMed Scopus (13) Google Scholar , 7 Harika R. Bermas K. Hughes C. et al. Cardiac arrest after liver transplantation in a patient with Takotsubo cardiomyopathy. Br J Anaesth. 2014; 112: 594-595 Crossref PubMed Scopus (16) Google Scholar , 8 Mukhtar A, Moharam H, Sarhan K, et al: Liver transplantation using dexmedetomidine in a patient with a history of Takotsubo cardiomyopathy. A A Case Rep 6(1):14-16, 2026 Google Scholar given the hyperdynamic state of circulation and high plasma catecholamine concentration in patients with advanced liver failure. 9 Wagener G. Kovalevskaya G. Minhaz M. et al. Vasopressin deficiency and vasodilatory state in end-stage liver disease. J Cardiothorac Vasc Anesth. 2011; 25: 665-670 Abstract Full Text Full Text PDF PubMed Scopus (44) Google Scholar , 10 Møller S. Henriksen J. Cirrhotic cardiomyopathy: A pathophysiological review of circulatory dysfunction in liver disease. Heart. 2002; 87: 9-15 Crossref PubMed Scopus (271) Google Scholar