Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2339930507', 'doi': None, 'title': 'Renal denervation: a new therapeutic approach for resistant hypertension.', 'display_name': 'Renal denervation: a new therapeutic approach for resistant hypertension.', 'publication_year': 2014, 'publication_date': '2014-01-01', 'ids': {'openalex': 'https://openalex.org/W2339930507', 'mag': '2339930507', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/25266531'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/25266531', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5102073075', 'display_name': 'Longxing Cao', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210120929', 'display_name': 'Zhujiang Hospital', 'ror': 'https://ror.org/02mhxa927', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210120929']}, {'id': 'https://openalex.org/I58200834', 'display_name': 'Southern Medical University', 'ror': 'https://ror.org/01vjw4z39', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I58200834']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Longxing Cao', 'raw_affiliation_strings': ['Cardiovascular Division, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong 510280, China.'], 'affiliations': [{'raw_affiliation_string': 'Cardiovascular Division, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong 510280, China.', 'institution_ids': ['https://openalex.org/I4210120929', 'https://openalex.org/I58200834']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5086961793', 'display_name': 'Qiang Fu', 'orcid': 'https://orcid.org/0000-0002-4523-608X'}, 'institutions': [{'id': 'https://openalex.org/I4210120929', 'display_name': 'Zhujiang Hospital', 'ror': 'https://ror.org/02mhxa927', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210120929']}, {'id': 'https://openalex.org/I58200834', 'display_name': 'Southern Medical University', 'ror': 'https://ror.org/01vjw4z39', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I58200834']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Qiang Fu', 'raw_affiliation_strings': ['Cardiovascular Division, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong 510280, China.'], 'affiliations': [{'raw_affiliation_string': 'Cardiovascular Division, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong 510280, China.', 'institution_ids': ['https://openalex.org/I4210120929', 'https://openalex.org/I58200834']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5069966705', 'display_name': 'Bing H. Wang', 'orcid': 'https://orcid.org/0000-0001-9580-2548'}, 'institutions': [{'id': 'https://openalex.org/I4210120929', 'display_name': 'Zhujiang Hospital', 'ror': 'https://ror.org/02mhxa927', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210120929']}, {'id': 'https://openalex.org/I58200834', 'display_name': 'Southern Medical University', 'ror': 'https://ror.org/01vjw4z39', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I58200834']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Bing Hui Wang', 'raw_affiliation_strings': ['Cardiovascular Division, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong 510280, China.'], 'affiliations': [{'raw_affiliation_string': 'Cardiovascular Division, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong 510280, China.', 'institution_ids': ['https://openalex.org/I4210120929', 'https://openalex.org/I58200834']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5100737126', 'display_name': 'Zhiliang Li', 'orcid': 'https://orcid.org/0000-0001-9868-1403'}, 'institutions': [{'id': 'https://openalex.org/I4210120929', 'display_name': 'Zhujiang Hospital', 'ror': 'https://ror.org/02mhxa927', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210120929']}, {'id': 'https://openalex.org/I58200834', 'display_name': 'Southern Medical University', 'ror': 'https://ror.org/01vjw4z39', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I58200834']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Zhiliang Li', 'raw_affiliation_strings': ['Cardiovascular Division, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong 510280, China.'], 'affiliations': [{'raw_affiliation_string': 'Cardiovascular Division, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong 510280, China.', 'institution_ids': ['https://openalex.org/I4210120929', 'https://openalex.org/I58200834']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 2000, 'currency': 'USD', 'value_usd': 2000, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.211, 'has_fulltext': False, 'cited_by_count': 1, 'citation_normalized_percentile': {'value': 0.52712, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 66, 'max': 73}, 'biblio': {'volume': '127', 'issue': '18', 'first_page': '3302', 'last_page': '8'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10144', 'display_name': 'Blood Pressure and Hypertension Studies', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10144', 'display_name': 'Blood Pressure and Hypertension Studies', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10745', 'display_name': 'Heart Rate Variability and Autonomic Control', 'score': 0.9988, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10924', 'display_name': 'Cardiovascular Health and Disease Prevention', 'score': 0.9944, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/renal-sympathetic-denervation', 'display_name': 'Renal sympathetic denervation', 'score': 0.753157}], 'concepts': [{'id': 'https://openalex.org/C2776805190', 'wikidata': 'https://www.wikidata.org/wiki/Q1187030', 'display_name': 'Denervation', 'level': 2, 'score': 0.94983244}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.8529644}, {'id': 'https://openalex.org/C2780177628', 'wikidata': 'https://www.wikidata.org/wiki/Q2186707', 'display_name': 'Renal sympathetic denervation', 'level': 4, 'score': 0.753157}, {'id': 'https://openalex.org/C84393581', 'wikidata': 'https://www.wikidata.org/wiki/Q82642', 'display_name': 'Blood pressure', 'level': 2, 'score': 0.5899305}, {'id': 'https://openalex.org/C535046627', 'wikidata': 'https://www.wikidata.org/wiki/Q30612', 'display_name': 'Clinical trial', 'level': 2, 'score': 0.57827795}, {'id': 'https://openalex.org/C2781267111', 'wikidata': 'https://www.wikidata.org/wiki/Q652297', 'display_name': 'Catheter', 'level': 2, 'score': 0.46890867}, {'id': 'https://openalex.org/C2780091579', 'wikidata': 'https://www.wikidata.org/wiki/Q9377', 'display_name': 'Kidney', 'level': 2, 'score': 0.42064655}, {'id': 'https://openalex.org/C3019558611', 'wikidata': 'https://www.wikidata.org/wiki/Q41861', 'display_name': 'Resistant hypertension', 'level': 3, 'score': 0.3955083}, {'id': 'https://openalex.org/C164705383', 'wikidata': 'https://www.wikidata.org/wiki/Q10379', 'display_name': 'Cardiology', 'level': 1, 'score': 0.38617396}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.38388738}, {'id': 'https://openalex.org/C177713679', 'wikidata': 'https://www.wikidata.org/wiki/Q679690', 'display_name': 'Intensive care medicine', 'level': 1, 'score': 0.37296766}, {'id': 'https://openalex.org/C141071460', 'wikidata': 'https://www.wikidata.org/wiki/Q40821', 'display_name': 'Surgery', 'level': 1, 'score': 0.30105793}], 'mesh': [{'descriptor_ui': 'D003714', 'descriptor_name': 'Denervation', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': True}, {'descriptor_ui': 'D007668', 'descriptor_name': 'Kidney', 'qualifier_ui': 'Q000294', 'qualifier_name': 'innervation', 'is_major_topic': True}, {'descriptor_ui': 'D001794', 'descriptor_name': 'Blood Pressure', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D001794', 'descriptor_name': 'Blood Pressure', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003714', 'descriptor_name': 'Denervation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006973', 'descriptor_name': 'Hypertension', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007668', 'descriptor_name': 'Kidney', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019635', 'descriptor_name': 'Neurosurgical Procedures', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013564', 'descriptor_name': 'Sympathetic Nervous System', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013564', 'descriptor_name': 'Sympathetic Nervous System', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/25266531', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.73, 'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 44, 'referenced_works': ['https://openalex.org/W1583834060', 'https://openalex.org/W1869619461', 'https://openalex.org/W1971796155', 'https://openalex.org/W1973921707', 'https://openalex.org/W1988122810', 'https://openalex.org/W1994487234', 'https://openalex.org/W1997818070', 'https://openalex.org/W1999969246', 'https://openalex.org/W2014035104', 'https://openalex.org/W2017873721', 'https://openalex.org/W2027113562', 'https://openalex.org/W2034941243', 'https://openalex.org/W2035597332', 'https://openalex.org/W2040380685', 'https://openalex.org/W2050817452', 'https://openalex.org/W2060989550', 'https://openalex.org/W2071279136', 'https://openalex.org/W2071378017', 'https://openalex.org/W2072601342', 'https://openalex.org/W2077128217', 'https://openalex.org/W2080450195', 'https://openalex.org/W2091660015', 'https://openalex.org/W2096346609', 'https://openalex.org/W2099897414', 'https://openalex.org/W2102620697', 'https://openalex.org/W2107831799', 'https://openalex.org/W2114127328', 'https://openalex.org/W2114707939', 'https://openalex.org/W2115461708', 'https://openalex.org/W2118458077', 'https://openalex.org/W2122826224', 'https://openalex.org/W2131490804', 'https://openalex.org/W2133416234', 'https://openalex.org/W2136504299', 'https://openalex.org/W2139200183', 'https://openalex.org/W2140347162', 'https://openalex.org/W2145427049', 'https://openalex.org/W2152641681', 'https://openalex.org/W2163665839', 'https://openalex.org/W2166180933', 'https://openalex.org/W2169491483', 'https://openalex.org/W2171400796', 'https://openalex.org/W2328058522', 'https://openalex.org/W2410500821'], 'related_works': ['https://openalex.org/W52172642', 'https://openalex.org/W2889636993', 'https://openalex.org/W2365383810', 'https://openalex.org/W2329555137', 'https://openalex.org/W2207553984', 'https://openalex.org/W2179104345', 'https://openalex.org/W2171476985', 'https://openalex.org/W2055834296', 'https://openalex.org/W2051474479', 'https://openalex.org/W2003892956'], 'abstract_inverted_index': {'To': [0], 'review': [1, 18], 'the': [2, 103, 115, 123, 129, 133, 142, 166, 176, 179, 182, 190, 216, 235, 238, 255, 258], 'advances': [3], 'in': [4, 16, 24, 59, 122, 135, 206, 215], 'studies': [5, 112], 'on': [6], 'renal': [7, 10, 29, 82, 90, 108, 120, 148, 196], 'denervation.References': [8], 'concerning': [9], 'denervation': [11, 30, 73, 121, 149, 197, 209], 'and': [12, 26, 46, 51, 83, 93, 117, 128, 172, 175, 187, 221], 'resistant': [13, 126, 219], 'hypertension': [14, 62, 127, 220], 'cited': [15], 'this': [17, 207], 'were': [19, 49], 'collected': [20], 'from': [21, 32], 'PubMed': [22], 'published': [23], 'English': [25], 'those': [27], 'of': [28, 35, 61, 89, 106, 119, 125, 132, 147, 168, 178, 194, 218, 232, 237, 257], 'devices': [31, 198], 'official': [33], 'websites': [34], 'device': [36], 'manufacturers': [37], 'up': [38], 'to': [39, 80, 102, 150, 153, 189, 253], 'January': [40], '2014.Articles': [41], 'with': [42], 'keywords': [43], '"renal': [44], 'denervation"': [45], '"resistant': [47], 'hypertension"': [48], 'selected.Renal': [50], 'systemic': [52, 84], 'sympathetic': [53, 70, 85, 91, 226], 'overactivity': [54, 86], 'plays': [55], 'an': [56], 'important': [57], 'role': [58], 'pathology': [60], 'as': [63, 65, 165], 'well': [64], 'other': [66, 136, 162, 222], 'diseases': [67, 223], 'characterized': [68, 224], 'by': [69, 87, 225], 'overactivity.': [71, 227], 'Renal': [72], 'is': [74, 203, 210, 240], 'a': [75, 211], 'new,': [76], 'catheter': [77], 'based': [78], 'procedure': [79, 134, 159, 239], 'reduce': [81], 'disruption': [88], 'efferent': [92], 'afferent': [94], 'nerves': [95], 'through': [96], 'radiofrequency': [97], 'or': [98], 'ultrasound': [99], 'energy': [100], 'delivered': [101], 'endoluminal': [104], 'surface': [105], 'both': [107], 'arteries.': [109], 'Although': [110], 'several': [111], 'have': [113], 'shown': [114], 'efficacy': [116, 171, 236], 'safety': [118, 173], 'treatment': [124], 'potential': [130], 'benefit': [131], 'diseases,': [137], 'Symplicity': [138], 'HTN': [139], '3': [140], 'study,': [141], 'most': [143], 'rigorous': [144], 'clinical': [145, 233, 248], 'trial': [146], 'date,': [151], 'failed': [152], 'meet': [154], 'its': [155, 229], 'primary': [156], 'endpoint.': [157], 'The': [158], 'also': [160, 204], 'has': [161], 'limitations': [163, 256], 'such': [164], 'lack': [167, 177], 'long': [169], 'term,': [170], 'data': [174], 'predictors': [180], 'for': [181], 'blood': [183], 'pressure': [184], 'lowering': [185], 'response': [186], 'nonresponse': [188], 'procedure.': [191, 259], 'An': [192], 'overview': [193], 'current': [195], 'holding': [199], 'Conformité': [200], 'Européenne': [201], 'mark': [202], 'included': [205], 'review.Renal': [208], 'promising': [212], 'therapeutic': [213], 'approach': [214], 'management': [217], 'In': [228], 'early': [230], 'stage': [231], 'application,': [234], 'still': [241, 251], 'controversial.': [242], 'Large': [243], 'scale,': [244], 'blind,': [245], 'randomized,': [246], 'controlled': [247], 'trials': [249], 'are': [250], 'necessary': [252], 'address': [254]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2339930507', 'counts_by_year': [{'year': 2015, 'cited_by_count': 1}], 'updated_date': '2024-12-17T06:47:21.668280', 'created_date': '2016-06-24'}