Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2339272779', 'doi': 'https://doi.org/10.1016/j.jalz.2015.06.853', 'title': 'P2‐311: <i>In vitro</i> characterization of s44858: A positive allosteric modulator of ampa receptors and GluN2B selective non‐competitive nmda receptors antagonist', 'display_name': 'P2‐311: <i>In vitro</i> characterization of s44858: A positive allosteric modulator of ampa receptors and GluN2B selective non‐competitive nmda receptors antagonist', 'publication_year': 2015, 'publication_date': '2015-07-01', 'ids': {'openalex': 'https://openalex.org/W2339272779', 'doi': 'https://doi.org/10.1016/j.jalz.2015.06.853', 'mag': '2339272779'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.jalz.2015.06.853', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1016/j.jalz.2015.06.853', 'source': {'id': 'https://openalex.org/S108427512', 'display_name': 'Alzheimer s & Dementia', 'issn_l': '1552-5260', 'issn': ['1552-5260', '1552-5279'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1016/j.jalz.2015.06.853', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5000301040', 'display_name': 'Laurence Danober', 'orcid': None}, 'institutions': [], 'countries': ['FR'], 'is_corresponding': True, 'raw_author_name': 'Laurence Danober', 'raw_affiliation_strings': ['Pôle Innovation Thérapeutique Neuropsychiatrie Institut de Recherches Servier Croissy‐sur-Seine France'], 'affiliations': [{'raw_affiliation_string': 'Pôle Innovation Thérapeutique Neuropsychiatrie Institut de Recherches Servier Croissy‐sur-Seine France', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5015436312', 'display_name': 'Jean‐Yves Thomas', 'orcid': None}, 'institutions': [], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Jean-Yves Thomas', 'raw_affiliation_strings': ['Pôle Innovation Thérapeutique Neuropsychiatrie Institut de Recherches Servier Croissy‐sur-Seine France'], 'affiliations': [{'raw_affiliation_string': 'Pôle Innovation Thérapeutique Neuropsychiatrie Institut de Recherches Servier Croissy‐sur-Seine France', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5036738983', 'display_name': 'Sylvie Challal', 'orcid': None}, 'institutions': [], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Sylvie Challal', 'raw_affiliation_strings': ['Pôle Innovation Thérapeutique Neuropsychiatrie Institut de Recherches Servier Croissy‐sur-Seine France'], 'affiliations': [{'raw_affiliation_string': 'Pôle Innovation Thérapeutique Neuropsychiatrie Institut de Recherches Servier Croissy‐sur-Seine France', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5046344654', 'display_name': 'Nathalie Rogez', 'orcid': None}, 'institutions': [], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Nathalie Rogez', 'raw_affiliation_strings': ['Pôle Innovation Thérapeutique Neuropsychiatrie Institut de Recherches Servier Croissy‐sur-Seine France'], 'affiliations': [{'raw_affiliation_string': 'Pôle Innovation Thérapeutique Neuropsychiatrie Institut de Recherches Servier Croissy‐sur-Seine France', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5018024173', 'display_name': 'Karine Albinet', 'orcid': None}, 'institutions': [], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Karine Albinet', 'raw_affiliation_strings': ['Pôle Innovation Thérapeutique Neuropsychiatrie Institut de Recherches Servier Croissy‐sur-Seine France'], 'affiliations': [{'raw_affiliation_string': 'Pôle Innovation Thérapeutique Neuropsychiatrie Institut de Recherches Servier Croissy‐sur-Seine France', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5064971320', 'display_name': 'Nadège Villain', 'orcid': None}, 'institutions': [], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Nadège Villain', 'raw_affiliation_strings': ['Pôle Innovation Thérapeutique Neuropsychiatrie Institut de Recherches Servier Croissy‐sur-Seine France'], 'affiliations': [{'raw_affiliation_string': 'Pôle Innovation Thérapeutique Neuropsychiatrie Institut de Recherches Servier Croissy‐sur-Seine France', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5005560729', 'display_name': 'Laétitia Mony', 'orcid': 'https://orcid.org/0000-0001-7753-6231'}, 'institutions': [{'id': 'https://openalex.org/I4210129409', 'display_name': "Institut de Biologie de l'École Normale Supérieure", 'ror': 'https://ror.org/03mxktp47', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I1294671590', 'https://openalex.org/I154526488', 'https://openalex.org/I2746051580', 'https://openalex.org/I29607241', 'https://openalex.org/I4210096427', 'https://openalex.org/I4210129409']}, {'id': 'https://openalex.org/I1294671590', 'display_name': 'Centre National de la Recherche Scientifique', 'ror': 'https://ror.org/02feahw73', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I1294671590']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Laétitia Mony', 'raw_affiliation_strings': ["Institut de Biologie de l'Ecole Normale Supérieure, CNRS-INSERM Paris France"], 'affiliations': [{'raw_affiliation_string': "Institut de Biologie de l'Ecole Normale Supérieure, CNRS-INSERM Paris France", 'institution_ids': ['https://openalex.org/I4210129409', 'https://openalex.org/I1294671590', 'https://openalex.org/I154526488']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5077631330', 'display_name': 'Pierre Paoletti', 'orcid': 'https://orcid.org/0000-0002-3681-4845'}, 'institutions': [{'id': 'https://openalex.org/I1294671590', 'display_name': 'Centre National de la Recherche Scientifique', 'ror': 'https://ror.org/02feahw73', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I1294671590']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}, {'id': 'https://openalex.org/I4210129409', 'display_name': "Institut de Biologie de l'École Normale Supérieure", 'ror': 'https://ror.org/03mxktp47', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I1294671590', 'https://openalex.org/I154526488', 'https://openalex.org/I2746051580', 'https://openalex.org/I29607241', 'https://openalex.org/I4210096427', 'https://openalex.org/I4210129409']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Pierre Paoletti', 'raw_affiliation_strings': ["Institut de Biologie de l'Ecole Normale Supérieure, CNRS-INSERM Paris France"], 'affiliations': [{'raw_affiliation_string': "Institut de Biologie de l'Ecole Normale Supérieure, CNRS-INSERM Paris France", 'institution_ids': ['https://openalex.org/I1294671590', 'https://openalex.org/I154526488', 'https://openalex.org/I4210129409']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5063992837', 'display_name': 'Daniel Bertrand', 'orcid': 'https://orcid.org/0000-0003-2057-7133'}, 'institutions': [{'id': 'https://openalex.org/I4210130222', 'display_name': 'HiQScreen (Switzerland)', 'ror': 'https://ror.org/02qjgmm73', 'country_code': 'CH', 'type': 'company', 'lineage': ['https://openalex.org/I4210130222']}], 'countries': ['CH'], 'is_corresponding': False, 'raw_author_name': 'Daniel Bertrand', 'raw_affiliation_strings': ['HiQScreen Vésenaz Geneva Switzerland'], 'affiliations': [{'raw_affiliation_string': 'HiQScreen Vésenaz Geneva Switzerland', 'institution_ids': ['https://openalex.org/I4210130222']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5026639308', 'display_name': 'Stéphanie Wagner', 'orcid': None}, 'institutions': [], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Stéphanie Wagner', 'raw_affiliation_strings': ['Neurofit, Illkirch, France'], 'affiliations': [{'raw_affiliation_string': 'Neurofit, Illkirch, France', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5025409839', 'display_name': 'Patrice Désos', 'orcid': 'https://orcid.org/0000-0002-6417-5614'}, 'institutions': [{'id': 'https://openalex.org/I4210135308', 'display_name': 'Servier (France)', 'ror': 'https://ror.org/034e7c066', 'country_code': 'FR', 'type': 'company', 'lineage': ['https://openalex.org/I4210135308']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Patrice Desos', 'raw_affiliation_strings': ['Pôle Expertise Recherche et Biopharmacie Institut de Recherches Servier Suresnes France'], 'affiliations': [{'raw_affiliation_string': 'Pôle Expertise Recherche et Biopharmacie Institut de Recherches Servier Suresnes France', 'institution_ids': ['https://openalex.org/I4210135308']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5110101726', 'display_name': 'Alex Cordi', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210135308', 'display_name': 'Servier (France)', 'ror': 'https://ror.org/034e7c066', 'country_code': 'FR', 'type': 'company', 'lineage': ['https://openalex.org/I4210135308']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Alex Cordi', 'raw_affiliation_strings': ['Pôle Expertise Recherche et Biopharmacie Institut de Recherches Servier Suresnes France'], 'affiliations': [{'raw_affiliation_string': 'Pôle Expertise Recherche et Biopharmacie Institut de Recherches Servier Suresnes France', 'institution_ids': ['https://openalex.org/I4210135308']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5064951739', 'display_name': 'Pierre Lestage', 'orcid': None}, 'institutions': [], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Pierre Lestage', 'raw_affiliation_strings': ['Pôle Innovation Thérapeutique Neuropsychiatrie Institut de Recherches Servier Croissy‐sur-Seine France'], 'affiliations': [{'raw_affiliation_string': 'Pôle Innovation Thérapeutique Neuropsychiatrie Institut de Recherches Servier Croissy‐sur-Seine France', 'institution_ids': []}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 5, 'corresponding_author_ids': ['https://openalex.org/A5000301040'], 'corresponding_institution_ids': [], 'apc_list': {'value': 4000, 'currency': 'USD', 'value_usd': 4000, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.131, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 1, 'citation_normalized_percentile': {'value': 0.365319, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 66, 'max': 73}, 'biblio': {'volume': '11', 'issue': '7S_Part_13', 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10077', 'display_name': 'Neuroscience and Neuropharmacology Research', 'score': 0.999, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10077', 'display_name': 'Neuroscience and Neuropharmacology Research', 'score': 0.999, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T13142', 'display_name': 'GABA and Rice Research', 'score': 0.9926, 'subfield': {'id': 'https://openalex.org/subfields/1110', 'display_name': 'Plant Science'}, 'field': {'id': 'https://openalex.org/fields/11', 'display_name': 'Agricultural and Biological Sciences'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11178', 'display_name': 'Receptor Mechanisms and Signaling', 'score': 0.9724, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/ifenprodil', 'display_name': 'Ifenprodil', 'score': 0.82467175}, {'id': 'https://openalex.org/keywords/kainate-receptor', 'display_name': 'Kainate receptor', 'score': 0.808812}, {'id': 'https://openalex.org/keywords/long-term-depression', 'display_name': 'Long-term depression', 'score': 0.719651}], 'concepts': [{'id': 'https://openalex.org/C160268369', 'wikidata': 'https://www.wikidata.org/wiki/Q295251', 'display_name': 'AMPA receptor', 'level': 4, 'score': 0.8587011}, {'id': 'https://openalex.org/C2780376555', 'wikidata': 'https://www.wikidata.org/wiki/Q5991156', 'display_name': 'Ifenprodil', 'level': 4, 'score': 0.82467175}, {'id': 'https://openalex.org/C189184402', 'wikidata': 'https://www.wikidata.org/wiki/Q3454536', 'display_name': 'Kainate receptor', 'level': 5, 'score': 0.808812}, {'id': 'https://openalex.org/C67018056', 'wikidata': 'https://www.wikidata.org/wiki/Q414896', 'display_name': 'NMDA receptor', 'level': 3, 'score': 0.79075164}, {'id': 'https://openalex.org/C73009533', 'wikidata': 'https://www.wikidata.org/wiki/Q1517140', 'display_name': 'Long-term depression', 'level': 5, 'score': 0.719651}, {'id': 'https://openalex.org/C61174792', 'wikidata': 'https://www.wikidata.org/wiki/Q420510', 'display_name': 'Glutamate receptor', 'level': 3, 'score': 0.59386367}, {'id': 'https://openalex.org/C169760540', 'wikidata': 'https://www.wikidata.org/wiki/Q207011', 'display_name': 'Neuroscience', 'level': 1, 'score': 0.50743455}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.46855006}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.44902903}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.40103844}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.37415338}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.35008302}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.2234709}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.jalz.2015.06.853', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1016/j.jalz.2015.06.853', 'source': {'id': 'https://openalex.org/S108427512', 'display_name': 'Alzheimer s & Dementia', 'issn_l': '1552-5260', 'issn': ['1552-5260', '1552-5279'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.jalz.2015.06.853', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1016/j.jalz.2015.06.853', 'source': {'id': 'https://openalex.org/S108427512', 'display_name': 'Alzheimer s & Dementia', 'issn_l': '1552-5260', 'issn': ['1552-5260', '1552-5279'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.7, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W48558193', 'https://openalex.org/W3112255947', 'https://openalex.org/W2626315778', 'https://openalex.org/W2602460352', 'https://openalex.org/W2120805776', 'https://openalex.org/W2083485910', 'https://openalex.org/W2063488873', 'https://openalex.org/W1993817377', 'https://openalex.org/W1988517145', 'https://openalex.org/W1988182535'], 'abstract_inverted_index': {'Modulation': [0], 'of': [1, 22, 36, 45, 75, 118, 204, 281, 318, 333, 340], 'the': [2, 37, 54, 110, 172, 209, 316, 331], 'glutamate': [3, 152, 244], 'receptors': [4, 29, 66, 160, 212, 283], 'has': [5], 'become': [6], 'prime': [7], 'targets': [8], 'for': [9, 171, 330], 'improving': [10], 'cognition': [11], 'in': [12, 49, 84, 290, 301, 315, 321, 337], 'Alzheimer,': [13], 'schizophrenia': [14], 'and': [15, 30, 64, 135, 158, 164, 198, 228, 245, 261, 284, 293, 296, 311], 'depression.': [16], 'S44858': [17, 146, 188, 205, 214, 232, 248, 255, 275, 288, 306, 324], 'presents': [18, 233, 289], 'a': [19, 277], 'unique': [20], 'mechanism': [21, 44], 'action,': [23], 'as': [24], 'it': [25], 'both': [26, 257], 'potentiates': [27], 'AMPA': [28, 134, 190, 211, 282], 'blocks': [31], 'NMDA': [32, 65, 159, 200, 230, 246], 'receptors.': [33, 231], 'The': [34], 'aim': [35], 'present': [38, 149], 'work': [39], 'was': [40, 67, 77, 106, 124, 206], 'to': [41, 53, 222], 'characterize': [42], 'its': [43], 'action': [46, 76], 'using': [47, 79], 'different': [48], 'vitro': [50, 291], 'approaches.': [51], 'Binding': [52], 'glutamate,': [55], 'ifenprodil,': [56], 'PCP': [57, 165], 'or': [58, 93, 97, 100, 184], 'glycine': [59, 163], 'sites': [60, 154], 'on': [61, 69, 113, 128, 141, 155, 226, 236], 'AMPA,': [62, 156], 'kainate': [63, 157, 196], 'determined': [68], 'rat': [70, 91, 114, 130, 143, 182, 237], 'brain': [71], 'membrane': [72], 'preparation.': [73], 'Mechanism': [74], 'examined': [78], 'two-electrodes': [80], 'voltage-clamp': [81], 'recordings': [82], 'conducted': [83], 'Xenopus': [85], 'laevis': [86], 'oocytes': [87, 179], 'injected': [88, 180], 'with': [89, 98, 181], 'either': [90], 'cortex': [92, 183], 'human': [94, 101, 185, 210, 229], 'hippocampal': [95, 144, 186], 'mRNAs': [96], 'rodent': [99, 227], 'GluN1/GluN2A-2B-2C-2D': [102], 'cDNAs.': [103], 'Neuroprotective': [104], 'activity': [105, 112], 'evaluated': [107], 'by': [108, 126], 'measuring': [109], 'LDH': [111], 'cortical': [115, 131], 'cultures.': [116, 132], 'Expression': [117], 'Brain-Derived': [119], 'Neurotrophic': [120], 'Factor': [121], '(BDNF)': [122], 'protein': [123], 'measured': [125], 'ELISA': [127], 'primary': [129, 238], 'Extracellular': [133], 'NMDA-mediated': [136, 266], 'postsynaptic': [137], 'responses': [138, 197, 260], 'were': [139], 'recorded': [140], 'Wistar': [142], 'slices.': [145], 'does': [147, 193], 'not': [148, 194], 'affinity': [150, 170], 'towards': [151, 162, 218], 'binding': [153, 166, 174], 'nor': [161], 'sites.': [167], 'A': [168], 'low': [169], 'ifenprodil': [173], 'site': [175], 'is': [176, 276], 'detected.': [177], 'On': [178], 'mRNA,': [187], 'increases': [189, 250, 256], 'responses,': [191], 'but': [192, 240], 'affect': [195], 'decreases': [199], 'responses.': [201, 268], 'Differential': [202], 'sensitivity': [203], 'uncovered': [207], 'at': [208], 'subtypes.': [213], 'displays': [215], 'also': [216, 249], 'selectivity': [217], 'GluN2B': [219, 285], 'subunits': [220, 225], 'compared': [221], 'other': [223], 'GluN2': [224], 'no': [234], 'toxicity': [235], 'cultures': [239], 'protects': [241], 'them': [242], 'from': [243], 'insults.': [247], 'AMPA-mediated': [251, 258], 'BDNF': [252], 'expression.': [253], 'Finally,': [254], 'synaptic': [259, 267, 298], 'long-term': [262], 'potentiation,': [263], 'while': [264], 'decreasing': [265], 'Taken': [269], 'together,': [270], 'these': [271], 'results': [272], 'revealed': [273], 'that': [274, 305], 'potent': [278], 'positive': [279], 'modulator': [280], 'selective': [286], 'antagonist.': [287], 'neurotrophic': [292], 'neuroprotective': [294], 'properties': [295, 313], 'enhances': [297], 'plasticity.': [299], 'Further': [300], 'vivo': [302], 'evaluations': [303], 'confirm': [304], 'possesses': [307], 'neuroprotective,': [308], 'cognitive': [309], 'enhancing': [310], 'antidepressant': [312], 'administration': [314], 'absence': [317], 'side': [319], 'effects': [320], 'rodents.': [322], 'Altogether,': [323], 'represents': [325], 'an': [326], 'attractive': [327], 'drug': [328], 'candidate': [329], 'treatment': [332], 'various': [334], 'CNS': [335], 'diseases': [336], 'which': [338], 'dysfunctions': [339], 'glutamatergic': [341], 'pathways': [342], 'have': [343], 'been': [344], 'implicated.': [345]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2339272779', 'counts_by_year': [{'year': 2017, 'cited_by_count': 1}], 'updated_date': '2024-12-26T04:25:49.697067', 'created_date': '2016-06-24'}