Title: A proposal on Cosmetic Safly Test: The Second Paper The Experimental Study on Comedogenecity of Cosmetics
Abstract: This present study was performed to evaluate the comedogenicity of several cosmetics. The test materials were applied to one ear canal of three rabbits daily for 6 weekdays for 2 weeks.The results were as follow :1) Among the 14 cosmetics, extremely weak comedogenicity was shown in one cosmetic, mild comedogenicity in 10 cosmetics and moderate comedogenicity in 3 cosmetics.2) There were no significant differences of comedogenicity among cosmetic species.3) The rabbit ear assay was a rapid, effective screening test for evaluation of comedogenicity of cosmetics.