Publication Information

{'id': 'https://openalex.org/W2336584292', 'doi': 'https://doi.org/10.1152/ajpcell.1987.253.1.c79', 'title': 'Diphenylamine-2-carboxylate blocks Cl(-)-HCO3- exchange in Necturus gallbladder epithelium', 'display_name': 'Diphenylamine-2-carboxylate blocks Cl(-)-HCO3- exchange in Necturus gallbladder epithelium', 'publication_year': 1987, 'publication_date': '1987-07-01', 'ids': {'openalex': 'https://openalex.org/W2336584292', 'doi': 'https://doi.org/10.1152/ajpcell.1987.253.1.c79', 'mag': '2336584292', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/3605330'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1152/ajpcell.1987.253.1.c79', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S62704344', 'display_name': 'AJP Cell Physiology', 'issn_l': '0363-6143', 'issn': ['0363-6143', '1522-1563'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320261', 'host_organization_name': 'American Physical Society', 'host_organization_lineage': ['https://openalex.org/P4310320261'], 'host_organization_lineage_names': ['American Physical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5005104920', 'display_name': 'Luis Reuss', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'L. Reuss', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5077488984', 'display_name': 'James Costantin', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'J. L. Costantin', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5082685437', 'display_name': 'Jeanne Bazile', 'orcid': 'https://orcid.org/0000-0001-5920-5279'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'J. E. Bazile', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 0, 'institutions_distinct_count': 0, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 3.273, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 48, 'citation_normalized_percentile': {'value': 0.676923, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 93, 'max': 94}, 'biblio': {'volume': '253', 'issue': '1', 'first_page': 'C79', 'last_page': 'C89'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11601', 'display_name': 'Neuroscience and Neural Engineering', 'score': 0.9945, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11601', 'display_name': 'Neuroscience and Neural Engineering', 'score': 0.9945, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12236', 'display_name': 'Photoreceptor and optogenetics research', 'score': 0.9928, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12813', 'display_name': 'Plant and Biological Electrophysiology Studies', 'score': 0.9926, 'subfield': {'id': 'https://openalex.org/subfields/1110', 'display_name': 'Plant Science'}, 'field': {'id': 'https://openalex.org/fields/11', 'display_name': 'Agricultural and Biological Sciences'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/necturus', 'display_name': 'Necturus', 'score': 0.89283574}, {'id': 'https://openalex.org/keywords/hyperpolarization', 'display_name': 'Hyperpolarization', 'score': 0.6528864}, {'id': 'https://openalex.org/keywords/apical-membrane', 'display_name': 'Apical membrane', 'score': 0.651132}, {'id': 'https://openalex.org/keywords/amiloride', 'display_name': 'Amiloride', 'score': 0.6201947}, {'id': 'https://openalex.org/keywords/intracellular-ph', 'display_name': 'Intracellular pH', 'score': 0.54724056}, {'id': 'https://openalex.org/keywords/epithelial-polarity', 'display_name': 'Epithelial polarity', 'score': 0.4673897}, {'id': 'https://openalex.org/keywords/diphenylamine', 'display_name': 'Diphenylamine', 'score': 0.43154934}, {'id': 'https://openalex.org/keywords/carboxylate', 'display_name': 'Carboxylate', 'score': 0.4189713}], 'concepts': [{'id': 'https://openalex.org/C2777144155', 'wikidata': 'https://www.wikidata.org/wiki/Q641652', 'display_name': 'Necturus', 'level': 3, 'score': 0.89283574}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.71978}, {'id': 'https://openalex.org/C79879829', 'wikidata': 'https://www.wikidata.org/wiki/Q5571762', 'display_name': 'Intracellular', 'level': 2, 'score': 0.69866204}, {'id': 'https://openalex.org/C131453863', 'wikidata': 'https://www.wikidata.org/wiki/Q1641079', 'display_name': 'Hyperpolarization (physics)', 'level': 3, 'score': 0.6528864}, {'id': 'https://openalex.org/C3018436504', 'wikidata': 'https://www.wikidata.org/wiki/Q29548', 'display_name': 'Apical membrane', 'level': 3, 'score': 0.651132}, {'id': 'https://openalex.org/C2779608910', 'wikidata': 'https://www.wikidata.org/wiki/Q419995', 'display_name': 'Amiloride', 'level': 3, 'score': 0.6201947}, {'id': 'https://openalex.org/C12554922', 'wikidata': 'https://www.wikidata.org/wiki/Q7100', 'display_name': 'Biophysics', 'level': 1, 'score': 0.5965589}, {'id': 'https://openalex.org/C134897140', 'wikidata': 'https://www.wikidata.org/wiki/Q6058355', 'display_name': 'Intracellular pH', 'level': 3, 'score': 0.54724056}, {'id': 'https://openalex.org/C181911157', 'wikidata': 'https://www.wikidata.org/wiki/Q389844', 'display_name': 'Membrane potential', 'level': 2, 'score': 0.53622967}, {'id': 'https://openalex.org/C39587587', 'wikidata': 'https://www.wikidata.org/wiki/Q5383698', 'display_name': 'Epithelial polarity', 'level': 3, 'score': 0.4673897}, {'id': 'https://openalex.org/C99975950', 'wikidata': 'https://www.wikidata.org/wiki/Q911011', 'display_name': 'Ion transporter', 'level': 3, 'score': 0.46429807}, {'id': 'https://openalex.org/C529295009', 'wikidata': 'https://www.wikidata.org/wiki/Q41301', 'display_name': 'Epithelium', 'level': 2, 'score': 0.43545085}, {'id': 'https://openalex.org/C2777040443', 'wikidata': 'https://www.wikidata.org/wiki/Q412265', 'display_name': 'Diphenylamine', 'level': 2, 'score': 0.43154934}, {'id': 'https://openalex.org/C2778074193', 'wikidata': 'https://www.wikidata.org/wiki/Q3498942', 'display_name': 'Carboxylate', 'level': 2, 'score': 0.4189713}, {'id': 'https://openalex.org/C41625074', 'wikidata': 'https://www.wikidata.org/wiki/Q176088', 'display_name': 'Membrane', 'level': 2, 'score': 0.40706497}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.38543248}, {'id': 'https://openalex.org/C71240020', 'wikidata': 'https://www.wikidata.org/wiki/Q186011', 'display_name': 'Stereochemistry', 'level': 1, 'score': 0.26860762}, {'id': 'https://openalex.org/C537181965', 'wikidata': 'https://www.wikidata.org/wiki/Q658', 'display_name': 'Sodium', 'level': 2, 'score': 0.24240139}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.18261844}, {'id': 'https://openalex.org/C66974803', 'wikidata': 'https://www.wikidata.org/wiki/Q10359898', 'display_name': 'Nuclear magnetic resonance spectroscopy', 'level': 2, 'score': 0.0778591}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C178790620', 'wikidata': 'https://www.wikidata.org/wiki/Q11351', 'display_name': 'Organic chemistry', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D002352', 'descriptor_name': 'Carrier Proteins', 'qualifier_ui': 'Q000037', 'qualifier_name': 'antagonists & inhibitors', 'is_major_topic': True}, {'descriptor_ui': 'D005704', 'descriptor_name': 'Gallbladder', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D062367', 'descriptor_name': 'ortho-Aminobenzoates', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001639', 'descriptor_name': 'Bicarbonates', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D001639', 'descriptor_name': 'Bicarbonates', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002352', 'descriptor_name': 'Carrier Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D027963', 'descriptor_name': 'Chloride-Bicarbonate Antiporters', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002712', 'descriptor_name': 'Chlorides', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D002712', 'descriptor_name': 'Chlorides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004553', 'descriptor_name': 'Electric Conductivity', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004848', 'descriptor_name': 'Epithelium', 'qualifier_ui': 'Q000648', 'qualifier_name': 'ultrastructure', 'is_major_topic': False}, {'descriptor_ui': 'D004848', 'descriptor_name': 'Epithelium', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D004848', 'descriptor_name': 'Epithelium', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D004848', 'descriptor_name': 'Epithelium', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005704', 'descriptor_name': 'Gallbladder', 'qualifier_ui': 'Q000648', 'qualifier_name': 'ultrastructure', 'is_major_topic': False}, {'descriptor_ui': 'D005704', 'descriptor_name': 'Gallbladder', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D005704', 'descriptor_name': 'Gallbladder', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006863', 'descriptor_name': 'Hydrogen-Ion Concentration', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007425', 'descriptor_name': 'Intracellular Membranes', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D007425', 'descriptor_name': 'Intracellular Membranes', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D007425', 'descriptor_name': 'Intracellular Membranes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009337', 'descriptor_name': 'Necturus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009994', 'descriptor_name': 'Osmolar Concentration', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013806', 'descriptor_name': 'Theophylline', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D013806', 'descriptor_name': 'Theophylline', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D062367', 'descriptor_name': 'ortho-Aminobenzoates', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1152/ajpcell.1987.253.1.c79', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S62704344', 'display_name': 'AJP Cell Physiology', 'issn_l': '0363-6143', 'issn': ['0363-6143', '1522-1563'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320261', 'host_organization_name': 'American Physical Society', 'host_organization_lineage': ['https://openalex.org/P4310320261'], 'host_organization_lineage_names': ['American Physical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/3605330', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/6', 'display_name': 'Clean water and sanitation', 'score': 0.55}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 18, 'referenced_works': ['https://openalex.org/W1554740034', 'https://openalex.org/W2005809724', 'https://openalex.org/W2023538182', 'https://openalex.org/W2027321089', 'https://openalex.org/W2032142018', 'https://openalex.org/W2058551605', 'https://openalex.org/W2063703812', 'https://openalex.org/W2067312729', 'https://openalex.org/W2073608912', 'https://openalex.org/W2076764566', 'https://openalex.org/W2094975220', 'https://openalex.org/W2110727946', 'https://openalex.org/W2125533687', 'https://openalex.org/W2130994101', 'https://openalex.org/W2132857448', 'https://openalex.org/W2151041721', 'https://openalex.org/W2161784987', 'https://openalex.org/W3185889544'], 'related_works': ['https://openalex.org/W2423611591', 'https://openalex.org/W2408325424', 'https://openalex.org/W2303328115', 'https://openalex.org/W2166015696', 'https://openalex.org/W2160463324', 'https://openalex.org/W2157455630', 'https://openalex.org/W2132857448', 'https://openalex.org/W2126914983', 'https://openalex.org/W2090080211', 'https://openalex.org/W2001720486'], 'abstract_inverted_index': {'Intracellular': [0], 'microelectrode': [1], 'techniques': [2], 'were': [3], 'employed': [4], 'to': [5, 25, 179], 'study': [6], 'the': [7, 26, 48, 73, 88, 118, 141, 154, 171, 185, 226, 241], 'effects': [8, 152], 'of': [9, 23, 35, 55, 72, 87, 144, 170, 225, 243, 258, 272], 'diphenylamine-2-carboxylate': [10], '(DPC)': [11], 'on': [12, 117, 140, 153], 'ion': [13], 'transport': [14], 'in': [15, 61, 67, 75, 90, 100, 157, 177, 181, 187, 205, 229, 252, 270, 275], 'Necturus': [16, 253], 'gallbladder': [17, 254], 'epithelium.': [18], 'Under': [19, 128], 'control': [20], 'conditions,': [21, 112, 130], 'addition': [22], 'DPC': [24, 46, 105, 131, 149, 201, 266], 'mucosal': [27, 82, 95, 164, 182, 194], 'bathing': [28], 'solution': [29, 83, 96], 'caused': [30, 47, 132, 167], 'a': [31, 223], 'concentration-dependent,': [32], 'reversible': [33], 'hyperpolarization': [34, 135], 'both': [36], 'cell': [37, 133], 'membranes': [38], 'with': [39, 53], 'no': [40, 115, 138, 151], 'measurable': [41], 'resistance': [42], 'changes.': [43], 'In': [44, 147], 'addition,': [45, 148], 'following': [49], 'effects,': [50], 'all': [51], 'consistent': [52], 'inhibition': [54], 'apical': [56, 119, 158], 'membrane': [57, 120, 134, 145, 159], 'Cl(-)-HCO3-': [58], 'exchange:': [59], 'fall': [60], 'intracellular': [62, 68], 'Cl-': [63, 122, 203], 'activity': [64], '(aCli),': [65], 'increase': [66], 'pH': [69], '(pHi),': [70], 'reduction': [71, 86], 'changes': [74, 156, 175, 180, 186], 'aCli': [76, 188], 'and': [77, 85, 184, 189, 219, 246, 263], 'pHi': [78, 91, 190], 'produced': [79, 92, 191], 'by': [80, 93, 125, 162, 192, 249], 'lowering': [81, 94, 193], '[Cl-],': [84, 165, 183], 'change': [89], '[HCO3-].': [97], 'Similar': [98], 'studies': [99, 271], 'theophylline-treated': [101], 'preparations': [102], 'indicate': [103], 'that': [104, 200, 240, 247], 'also': [106], 'inhibits': [107], 'anion': [108, 273], 'exchange': [109, 274], 'under': [110], 'these': [111, 129], 'but': [113, 136, 166], 'has': [114], 'effect': [116, 139], 'electrodiffusive': [121], 'permeability': [123], 'induced': [124, 248], 'cyclic': [126, 250], 'AMP.': [127], 'had': [137, 150], 'apparent': [142], 'ratio': [143], 'resistances.': [146], 'rapid': [155, 264], 'voltage': [160, 174], 'elicited': [161], 'altering': [163], 'significant': [168], 'reductions': [169], 'slower,': [172], 'secondary': [173], 'observed': [176], 'response': [178], '[Cl-].': [195], 'Because': [196, 257], 'others': [197], 'have': [198], 'demonstrated': [199], 'blocks': [202], 'channels': [204, 245], 'other': [206, 276], 'epithelia': [207], '(Distefano,': [208], 'A.,': [209], 'M.': [210], 'Wittner,': [211], 'E.': [212], 'Schlatter,': [213], 'H.': [214, 217], 'J.': [215], 'Lang,': [216], 'Englert,': [218], 'R.': [220], 'Greger.': [221], 'Diphenylamine-2-carboxylate,': [222], 'blocker': [224], 'Cl(-)-conductive': [227], 'pathway': [228], 'Cl(-)-transporting': [230], 'epithelia.': [231], 'Pfluegers++': [232], 'Arch.': [233], '405:': [234], 'S95-S100,': [235], '1985),': [236], 'it': [237], 'is': [238], 'possible': [239], 'structures': [242], 'those': [244], 'AMP': [251], 'are': [255], 'different.': [256], 'its': [259], 'relatively': [260], 'high': [261], 'affinity': [262], 'reversibility,': [265], 'may': [267], 'become': [268], 'useful': [269], 'cells.': [277]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2336584292', 'counts_by_year': [{'year': 2016, 'cited_by_count': 1}], 'updated_date': '2024-12-11T09:35:14.299885', 'created_date': '2016-06-24'}