Title: Aminoglycoside nephrotoxicity in dogs: dependence on drug, dose and regimen.
Abstract: In female mongrel dogs nephrotoxicity of three aminoglycosides (gentamicin, tobramycin and netilmicin) was compared with relation to the cortical aminoglycoside concentration. A standard regimen of 45 mg/kg/day with constant intravenous infusion and once daily dosing of each aminoglycoside was used, and in subsequent dogs netilmicin daily dose was increased to an average of 73 mg/kg/day.
Publication Year: 1980
Publication Date: 1980-01-01
Language: en
Type: article
Indexed In: ['pubmed']
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Cited By Count: 4
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