Publication Information

{'id': 'https://openalex.org/W2335240697', 'doi': 'https://doi.org/10.1021/acs.jafc.5b00065', 'title': 'Production of Dihydroxylated Betalains and Dopamine in Cell Suspension Cultures of <i>Celosia argentea</i> var. <i>plumosa</i>', 'display_name': 'Production of Dihydroxylated Betalains and Dopamine in Cell Suspension Cultures of <i>Celosia argentea</i> var. <i>plumosa</i>', 'publication_year': 2015, 'publication_date': '2015-03-01', 'ids': {'openalex': 'https://openalex.org/W2335240697', 'doi': 'https://doi.org/10.1021/acs.jafc.5b00065', 'mag': '2335240697', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/25727687'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1021/acs.jafc.5b00065', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S134644764', 'display_name': 'Journal of Agricultural and Food Chemistry', 'issn_l': '0021-8561', 'issn': ['0021-8561', '1520-5118'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320006', 'host_organization_name': 'American Chemical Society', 'host_organization_lineage': ['https://openalex.org/P4310320006'], 'host_organization_lineage_names': ['American Chemical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5052977113', 'display_name': 'Berenice Guadarrama-Flores', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I200362191', 'display_name': 'Universidad Autónoma Metropolitana', 'ror': 'https://ror.org/02kta5139', 'country_code': 'MX', 'type': 'education', 'lineage': ['https://openalex.org/I200362191']}, {'id': 'https://openalex.org/I59361560', 'display_name': 'Instituto Politécnico Nacional', 'ror': 'https://ror.org/059sp8j34', 'country_code': 'MX', 'type': 'education', 'lineage': ['https://openalex.org/I59361560']}, {'id': 'https://openalex.org/I80180929', 'display_name': 'Universidad de Murcia', 'ror': 'https://ror.org/03p3aeb86', 'country_code': 'ES', 'type': 'education', 'lineage': ['https://openalex.org/I80180929']}], 'countries': ['ES', 'MX'], 'is_corresponding': False, 'raw_author_name': 'Berenice Guadarrama-Flores', 'raw_affiliation_strings': ['Departamento\rde Bioquímica y Biología Molecular A, Unidad Docente\rde Biología, Facultad de Veterinaria, Regional Campus of International\rExcellence “Campus Mare Nostrum”, Universidad de Murcia, E-30100 Espinardo, Murcia, Spain', 'Departamento\rde Biotecnología, Centro de Desarrollo de Productos Bióticos\r(CeProBi), Instituto Politécnico Nacional, San Isidro, Yautepec, Morelos, Mexico', 'Departamento\rde Biotecnología, Universidad Autónoma Metropolitana-Unidad Iztapalapa, Col. Vicentina, 09340 Ciudad de México, Federal District, Mexico'], 'affiliations': [{'raw_affiliation_string': 'Departamento\rde Biotecnología, Universidad Autónoma Metropolitana-Unidad Iztapalapa, Col. Vicentina, 09340 Ciudad de México, Federal District, Mexico', 'institution_ids': ['https://openalex.org/I200362191']}, {'raw_affiliation_string': 'Departamento\rde Biotecnología, Centro de Desarrollo de Productos Bióticos\r(CeProBi), Instituto Politécnico Nacional, San Isidro, Yautepec, Morelos, Mexico', 'institution_ids': ['https://openalex.org/I59361560']}, {'raw_affiliation_string': 'Departamento\rde Bioquímica y Biología Molecular A, Unidad Docente\rde Biología, Facultad de Veterinaria, Regional Campus of International\rExcellence “Campus Mare Nostrum”, Universidad de Murcia, E-30100 Espinardo, Murcia, Spain', 'institution_ids': ['https://openalex.org/I80180929']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5010516425', 'display_name': 'Mario Rodrı́guez-Monroy', 'orcid': 'https://orcid.org/0000-0001-6201-7594'}, 'institutions': [{'id': 'https://openalex.org/I59361560', 'display_name': 'Instituto Politécnico Nacional', 'ror': 'https://ror.org/059sp8j34', 'country_code': 'MX', 'type': 'education', 'lineage': ['https://openalex.org/I59361560']}], 'countries': ['MX'], 'is_corresponding': False, 'raw_author_name': 'Mario Rodríguez-Monroy', 'raw_affiliation_strings': ['Departamento\rde Biotecnología, Centro de Desarrollo de Productos Bióticos\r(CeProBi), Instituto Politécnico Nacional, San Isidro, Yautepec, Morelos, Mexico'], 'affiliations': [{'raw_affiliation_string': 'Departamento\rde Biotecnología, Centro de Desarrollo de Productos Bióticos\r(CeProBi), Instituto Politécnico Nacional, San Isidro, Yautepec, Morelos, Mexico', 'institution_ids': ['https://openalex.org/I59361560']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5076255091', 'display_name': 'Francisco Cruz‐Sosa', 'orcid': 'https://orcid.org/0000-0002-7127-7264'}, 'institutions': [{'id': 'https://openalex.org/I200362191', 'display_name': 'Universidad Autónoma Metropolitana', 'ror': 'https://ror.org/02kta5139', 'country_code': 'MX', 'type': 'education', 'lineage': ['https://openalex.org/I200362191']}], 'countries': ['MX'], 'is_corresponding': False, 'raw_author_name': 'Francisco Cruz-Sosa', 'raw_affiliation_strings': ['Departamento\rde Biotecnología, Universidad Autónoma Metropolitana-Unidad Iztapalapa, Col. Vicentina, 09340 Ciudad de México, Federal District, Mexico'], 'affiliations': [{'raw_affiliation_string': 'Departamento\rde Biotecnología, Universidad Autónoma Metropolitana-Unidad Iztapalapa, Col. Vicentina, 09340 Ciudad de México, Federal District, Mexico', 'institution_ids': ['https://openalex.org/I200362191']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5019913842', 'display_name': 'Francisco García‐Carmona', 'orcid': 'https://orcid.org/0000-0002-1318-7690'}, 'institutions': [{'id': 'https://openalex.org/I80180929', 'display_name': 'Universidad de Murcia', 'ror': 'https://ror.org/03p3aeb86', 'country_code': 'ES', 'type': 'education', 'lineage': ['https://openalex.org/I80180929']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'Francisco García-Carmona', 'raw_affiliation_strings': ['Departamento\rde Bioquímica y Biología Molecular A, Unidad Docente\rde Biología, Facultad de Veterinaria, Regional Campus of International\rExcellence “Campus Mare Nostrum”, Universidad de Murcia, E-30100 Espinardo, Murcia, Spain'], 'affiliations': [{'raw_affiliation_string': 'Departamento\rde Bioquímica y Biología Molecular A, Unidad Docente\rde Biología, Facultad de Veterinaria, Regional Campus of International\rExcellence “Campus Mare Nostrum”, Universidad de Murcia, E-30100 Espinardo, Murcia, Spain', 'institution_ids': ['https://openalex.org/I80180929']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5102830748', 'display_name': 'Fernando Gandía‐Herrero', 'orcid': 'https://orcid.org/0000-0003-4389-3454'}, 'institutions': [{'id': 'https://openalex.org/I80180929', 'display_name': 'Universidad de Murcia', 'ror': 'https://ror.org/03p3aeb86', 'country_code': 'ES', 'type': 'education', 'lineage': ['https://openalex.org/I80180929']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'Fernando Gandía-Herrero', 'raw_affiliation_strings': ['Departamento\rde Bioquímica y Biología Molecular A, Unidad Docente\rde Biología, Facultad de Veterinaria, Regional Campus of International\rExcellence “Campus Mare Nostrum”, Universidad de Murcia, E-30100 Espinardo, Murcia, Spain'], 'affiliations': [{'raw_affiliation_string': 'Departamento\rde Bioquímica y Biología Molecular A, Unidad Docente\rde Biología, Facultad de Veterinaria, Regional Campus of International\rExcellence “Campus Mare Nostrum”, Universidad de Murcia, E-30100 Espinardo, Murcia, Spain', 'institution_ids': ['https://openalex.org/I80180929']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 3, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 6.2, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 42, 'citation_normalized_percentile': {'value': 0.934689, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 95, 'max': 96}, 'biblio': {'volume': '63', 'issue': '10', 'first_page': '2741', 'last_page': '2749'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12330', 'display_name': 'Botanical Research and Applications', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1106', 'display_name': 'Food Science'}, 'field': {'id': 'https://openalex.org/fields/11', 'display_name': 'Agricultural and Biological Sciences'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12330', 'display_name': 'Botanical Research and Applications', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1106', 'display_name': 'Food Science'}, 'field': {'id': 'https://openalex.org/fields/11', 'display_name': 'Agricultural and Biological Sciences'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T13124', 'display_name': 'Chemical synthesis and alkaloids', 'score': 0.9546, 'subfield': {'id': 'https://openalex.org/subfields/1605', 'display_name': 'Organic Chemistry'}, 'field': {'id': 'https://openalex.org/fields/16', 'display_name': 'Chemistry'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T12832', 'display_name': 'Biocrusts and Microbial Ecology', 'score': 0.937, 'subfield': {'id': 'https://openalex.org/subfields/1105', 'display_name': 'Ecology, Evolution, Behavior and Systematics'}, 'field': {'id': 'https://openalex.org/fields/11', 'display_name': 'Agricultural and Biological Sciences'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/suspension-culture', 'display_name': 'Suspension culture', 'score': 0.47870567}, {'id': 'https://openalex.org/keywords/biological-pigment', 'display_name': 'Biological pigment', 'score': 0.42219776}], 'concepts': [{'id': 'https://openalex.org/C64584667', 'wikidata': 'https://www.wikidata.org/wiki/Q161179', 'display_name': 'Pigment', 'level': 2, 'score': 0.625151}, {'id': 'https://openalex.org/C59822182', 'wikidata': 'https://www.wikidata.org/wiki/Q441', 'display_name': 'Botany', 'level': 1, 'score': 0.52214915}, {'id': 'https://openalex.org/C31903555', 'wikidata': 'https://www.wikidata.org/wiki/Q1637030', 'display_name': 'Food science', 'level': 1, 'score': 0.5013957}, {'id': 'https://openalex.org/C2993787908', 'wikidata': 'https://www.wikidata.org/wiki/Q189111', 'display_name': 'Suspension culture', 'level': 3, 'score': 0.47870567}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.45964953}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.42474028}, {'id': 'https://openalex.org/C152452498', 'wikidata': 'https://www.wikidata.org/wiki/Q910979', 'display_name': 'Biological pigment', 'level': 3, 'score': 0.42219776}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.40937853}, {'id': 'https://openalex.org/C81885089', 'wikidata': 'https://www.wikidata.org/wiki/Q189082', 'display_name': 'Cell culture', 'level': 2, 'score': 0.39218974}, {'id': 'https://openalex.org/C178790620', 'wikidata': 'https://www.wikidata.org/wiki/Q11351', 'display_name': 'Organic chemistry', 'level': 1, 'score': 0.10940376}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D050858', 'descriptor_name': 'Betalains', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': True}, {'descriptor_ui': 'D034762', 'descriptor_name': 'Celosia', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D004298', 'descriptor_name': 'Dopamine', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': True}, {'descriptor_ui': 'D050858', 'descriptor_name': 'Betalains', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D050858', 'descriptor_name': 'Betalains', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D002478', 'descriptor_name': 'Cells, Cultured', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D034762', 'descriptor_name': 'Celosia', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D034762', 'descriptor_name': 'Celosia', 'qualifier_ui': 'Q000254', 'qualifier_name': 'growth & development', 'is_major_topic': False}, {'descriptor_ui': 'D034762', 'descriptor_name': 'Celosia', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D004298', 'descriptor_name': 'Dopamine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004298', 'descriptor_name': 'Dopamine', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1021/acs.jafc.5b00065', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S134644764', 'display_name': 'Journal of Agricultural and Food Chemistry', 'issn_l': '0021-8561', 'issn': ['0021-8561', '1520-5118'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320006', 'host_organization_name': 'American Chemical Society', 'host_organization_lineage': ['https://openalex.org/P4310320006'], 'host_organization_lineage_names': ['American Chemical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/25727687', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [{'funder': 'https://openalex.org/F4320321739', 'funder_display_name': 'Consejo Nacional de Ciencia y Tecnología', 'award_id': None}, {'funder': 'https://openalex.org/F4320322930', 'funder_display_name': 'Ministerio de Ciencia e Innovación', 'award_id': 'AGL2011-25023'}, {'funder': 'https://openalex.org/F4320335322', 'funder_display_name': 'European Regional Development Fund', 'award_id': 'AGL2011-25023'}], 'datasets': [], 'versions': [], 'referenced_works_count': 52, 'referenced_works': ['https://openalex.org/W127900425', 'https://openalex.org/W1488176541', 'https://openalex.org/W1531960817', 'https://openalex.org/W1921289352', 'https://openalex.org/W1965392694', 'https://openalex.org/W1966833601', 'https://openalex.org/W1976178786', 'https://openalex.org/W1980897862', 'https://openalex.org/W1989109407', 'https://openalex.org/W2000721301', 'https://openalex.org/W2000742397', 'https://openalex.org/W2002834809', 'https://openalex.org/W2005240259', 'https://openalex.org/W2009632953', 'https://openalex.org/W2013608879', 'https://openalex.org/W2013646420', 'https://openalex.org/W2013991644', 'https://openalex.org/W2016352304', 'https://openalex.org/W2017894343', 'https://openalex.org/W2018481198', 'https://openalex.org/W2024556021', 'https://openalex.org/W2025431637', 'https://openalex.org/W2030223082', 'https://openalex.org/W2035102929', 'https://openalex.org/W2036402183', 'https://openalex.org/W2040455828', 'https://openalex.org/W2045338678', 'https://openalex.org/W2049275627', 'https://openalex.org/W2049670007', 'https://openalex.org/W2053249752', 'https://openalex.org/W2057946202', 'https://openalex.org/W2062392870', 'https://openalex.org/W2079251575', 'https://openalex.org/W2079993770', 'https://openalex.org/W2080013806', 'https://openalex.org/W2080955963', 'https://openalex.org/W2087188756', 'https://openalex.org/W2091362485', 'https://openalex.org/W2094411298', 'https://openalex.org/W2094677232', 'https://openalex.org/W2126516757', 'https://openalex.org/W2137194873', 'https://openalex.org/W2141836696', 'https://openalex.org/W2153606005', 'https://openalex.org/W2161128598', 'https://openalex.org/W2163408725', 'https://openalex.org/W2165951738', 'https://openalex.org/W2166022684', 'https://openalex.org/W2312575603', 'https://openalex.org/W2331137349', 'https://openalex.org/W2740675302', 'https://openalex.org/W3140941267'], 'related_works': ['https://openalex.org/W3200346042', 'https://openalex.org/W2393608112', 'https://openalex.org/W2393239754', 'https://openalex.org/W2388297687', 'https://openalex.org/W2380329478', 'https://openalex.org/W2364605177', 'https://openalex.org/W2348208033', 'https://openalex.org/W230925822', 'https://openalex.org/W2092275313', 'https://openalex.org/W1973182096'], 'abstract_inverted_index': {'Betalains': [0], 'are': [1, 52], 'plant': [2, 74, 97], 'pigments': [3, 62], 'of': [4, 72, 114, 132, 156, 164, 172, 175, 183], 'hydrophilic': [5], 'nature': [6], 'with': [7, 26, 57, 95, 125, 142, 161], 'demonstrated': [8], 'chemopreventive': [9], 'potential': [10], 'in': [11, 66, 117], 'cancer': [12], 'cell': [13, 67, 82, 173], 'lines': [14], 'and': [15, 35, 43, 46, 50, 79, 85, 91, 103, 120, 140, 166], 'animal': [16], 'models.': [17], 'Among': [18], 'the': [19, 32, 47, 53, 73, 96, 118, 123, 157, 162, 170], 'betalains,': [20], 'those': [21], 'containing': [22], 'an': [23], 'aromatic': [24], 'moiety': [25], 'two': [27], 'free': [28, 36], 'hydroxyl': [29], 'groups': [30], 'possess': [31], 'strongest': [33], 'antioxidant': [34], 'radical': [37], 'scavenging': [38], 'activities.': [39], 'The': [40, 153], 'betaxanthins': [41], 'dopaxanthin': [42], 'miraxanthin': [44], 'V': [45], 'betacyanins': [48], 'betanidin': [49], 'decarboxy-betanidin': [51], 'only': [54], 'natural': [55], 'betalains': [56, 116, 159], 'catecholic': [58], 'substructures.': [59], 'These': [60], 'four': [61], 'have': [63], 'been': [64], 'produced': [65], 'cultures': [68, 110, 174], 'established': [69], 'from': [70], 'hypocotyls': [71], 'Celosia': [75], 'argentea.': [76], 'Two': [77], 'stable': [78, 181], 'differentially': [80], 'colored': [81], 'lines,': [83], 'yellow': [84], 'red,': [86], 'were': [87, 150], 'maintained': [88], 'on': [89], 'Murashige': [90], 'Skoog': [92], 'medium': [93, 124], 'supplemented': [94], 'growth': [98], 'regulators': [99], '6-benzylaminopurine': [100], '(6.66': [101], 'μM)': [102], '2,4-dichlorophenoxyacetic': [104], 'acid': [105, 139, 168], '(6.79': [106], 'μM).': [107], 'Derived': [108], 'suspension': [109], 'showed': [111], 'increased': [112], 'production': [113, 163], 'dihydroxylated': [115], 'cells': [119], 'secreted': [121], 'to': [122, 145, 178], 'a': [126, 180], 'maximum': [127], 'reached': [128], 'after': [129], '8': [130], 'days': [131], 'culture.': [133], 'In': [134], 'addition,': [135], 'precursor': [136], 'molecules': [137], 'betalamic': [138, 167], 'dopamine,': [141], 'content': [143], 'up': [144], '42.08': [146], 'mg/g': [147], 'dry': [148], 'weight,': [149], 'also': [151], 'obtained.': [152], 'joint': [154], 'presence': [155], 'bioactive': [158], 'together': [160], 'dopamine': [165], 'show': [169], 'ability': [171], 'C.': [176], 'argentea': [177], 'become': [179], 'source': [182], 'valuable': [184], 'phytochemicals.': [185]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2335240697', 'counts_by_year': [{'year': 2024, 'cited_by_count': 4}, {'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 4}, {'year': 2021, 'cited_by_count': 5}, {'year': 2020, 'cited_by_count': 7}, {'year': 2019, 'cited_by_count': 4}, {'year': 2018, 'cited_by_count': 7}, {'year': 2017, 'cited_by_count': 5}, {'year': 2016, 'cited_by_count': 3}], 'updated_date': '2024-12-26T11:19:54.345974', 'created_date': '2016-06-24'}