Title: Synthesis of New Organocatalysts and their Application on Asymmetric Green Epoxidation of , -Unsaturated Aldehydes
Abstract: The enantioselective synthesis of chiral compounds is an important research area. In this context, organocatalysis is an useful tool in the synthesis of building blocks under conditions that comply with the principles of green chemistry. In this work, we highlight the synthesis of new organocatalysts from proline and their application in the enantioselective synthesis of epoxialdehydes in aqueous solvent. These compounds are widely used as intermediates in the synthesis of biologically active natural products (Figure 1).