Title: Does the mTOR inhibitor everolimus influence the course of epilepsy in children with tuberous sclerosis complex?
Abstract: Aims: Tuberous sclerosis complex (TSC) is a neurocutaneous syndrome affecting the skin, brain, kidneys, and heart. The recently approved mTOR inhibitor everolimus acts directly on the pathomechanism of the disorder. Studies documenting the effectiveness of everolimus in treating the subependymal giant cell astrocytoma (SEGA) also indicate an improvement in frequently therapy-resistant epilepsy.
Publication Year: 2013
Publication Date: 2013-03-26
Language: en
Type: article
Indexed In: ['crossref']
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