Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2328293836', 'doi': 'https://doi.org/10.1021/jf502557f', 'title': 'Effects of Intestinal Microbiota on the Bioavailability of Geniposide in Rats', 'display_name': 'Effects of Intestinal Microbiota on the Bioavailability of Geniposide in Rats', 'publication_year': 2014, 'publication_date': '2014-09-26', 'ids': {'openalex': 'https://openalex.org/W2328293836', 'doi': 'https://doi.org/10.1021/jf502557f', 'mag': '2328293836', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/25257195'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1021/jf502557f', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S134644764', 'display_name': 'Journal of Agricultural and Food Chemistry', 'issn_l': '0021-8561', 'issn': ['0021-8561', '1520-5118'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320006', 'host_organization_name': 'American Chemical Society', 'host_organization_lineage': ['https://openalex.org/P4310320006'], 'host_organization_lineage_names': ['American Chemical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'letter', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5038229401', 'display_name': 'Ming Jin', 'orcid': 'https://orcid.org/0000-0002-3324-8948'}, 'institutions': [{'id': 'https://openalex.org/I4575257', 'display_name': 'Hanyang University', 'ror': 'https://ror.org/046865y68', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I4575257']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Ming Ji Jin', 'raw_affiliation_strings': ['Institute\rof Pharmaceutical Science and Technology and College of Pharmacy, Hanyang University, Ansan, Gyeonggi-do, Korea'], 'affiliations': [{'raw_affiliation_string': 'Institute\rof Pharmaceutical Science and Technology and College of Pharmacy, Hanyang University, Ansan, Gyeonggi-do, Korea', 'institution_ids': ['https://openalex.org/I4575257']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5034190142', 'display_name': 'In‐Sook Kim', 'orcid': 'https://orcid.org/0000-0003-0600-8268'}, 'institutions': [{'id': 'https://openalex.org/I4575257', 'display_name': 'Hanyang University', 'ror': 'https://ror.org/046865y68', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I4575257']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'In Sook Kim', 'raw_affiliation_strings': ['Institute\rof Pharmaceutical Science and Technology and College of Pharmacy, Hanyang University, Ansan, Gyeonggi-do, Korea'], 'affiliations': [{'raw_affiliation_string': 'Institute\rof Pharmaceutical Science and Technology and College of Pharmacy, Hanyang University, Ansan, Gyeonggi-do, Korea', 'institution_ids': ['https://openalex.org/I4575257']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100454672', 'display_name': 'Dong‐Hyun Kim', 'orcid': 'https://orcid.org/0000-0002-3689-2130'}, 'institutions': [{'id': 'https://openalex.org/I35928602', 'display_name': 'Kyung Hee University', 'ror': 'https://ror.org/01zqcg218', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I35928602']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Dong-Hyun Kim', 'raw_affiliation_strings': ['Department\rof Pharmacy, College of Pharmacy, Kyung Hee University, Dongdaemun-gu,\rSeoul, Korea'], 'affiliations': [{'raw_affiliation_string': 'Department\rof Pharmacy, College of Pharmacy, Kyung Hee University, Dongdaemun-gu,\rSeoul, Korea', 'institution_ids': ['https://openalex.org/I35928602']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5068541222', 'display_name': 'Hye Hyun Yoo', 'orcid': 'https://orcid.org/0000-0001-8282-852X'}, 'institutions': [{'id': 'https://openalex.org/I4575257', 'display_name': 'Hanyang University', 'ror': 'https://ror.org/046865y68', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I4575257']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Hye Hyun Yoo', 'raw_affiliation_strings': ['Institute\rof Pharmaceutical Science and Technology and College of Pharmacy, Hanyang University, Ansan, Gyeonggi-do, Korea'], 'affiliations': [{'raw_affiliation_string': 'Institute\rof Pharmaceutical Science and Technology and College of Pharmacy, Hanyang University, Ansan, Gyeonggi-do, Korea', 'institution_ids': ['https://openalex.org/I4575257']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': None, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 30, 'citation_normalized_percentile': {'value': 0.99061, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 93, 'max': 94}, 'biblio': {'volume': '62', 'issue': '40', 'first_page': '9632', 'last_page': '9636'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12817', 'display_name': 'Pharmacological Effects of Natural Compounds', 'score': 0.9989, 'subfield': {'id': 'https://openalex.org/subfields/3004', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/30', 'display_name': 'Pharmacology, Toxicology and Pharmaceutics'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12817', 'display_name': 'Pharmacological Effects of Natural Compounds', 'score': 0.9989, 'subfield': {'id': 'https://openalex.org/subfields/3004', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/30', 'display_name': 'Pharmacology, Toxicology and Pharmaceutics'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10066', 'display_name': 'Gut microbiota and health', 'score': 0.9984, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10836', 'display_name': 'Metabolomics and Mass Spectrometry Studies', 'score': 0.9983, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C181389837', 'wikidata': 'https://www.wikidata.org/wiki/Q461809', 'display_name': 'Bioavailability', 'level': 2, 'score': 0.8771101}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.41597277}, {'id': 'https://openalex.org/C31903555', 'wikidata': 'https://www.wikidata.org/wiki/Q1637030', 'display_name': 'Food science', 'level': 1, 'score': 0.3954294}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.30668825}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.28972012}], 'mesh': [{'descriptor_ui': 'D007422', 'descriptor_name': 'Intestines', 'qualifier_ui': 'Q000382', 'qualifier_name': 'microbiology', 'is_major_topic': True}, {'descriptor_ui': 'D007422', 'descriptor_name': 'Intestines', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D039823', 'descriptor_name': 'Iridoids', 'qualifier_ui': 'Q000493', 'qualifier_name': 'pharmacokinetics', 'is_major_topic': True}, {'descriptor_ui': 'D064307', 'descriptor_name': 'Microbiota', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000284', 'descriptor_name': 'Administration, Oral', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001682', 'descriptor_name': 'Biological Availability', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007422', 'descriptor_name': 'Intestines', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D039823', 'descriptor_name': 'Iridoids', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D039823', 'descriptor_name': 'Iridoids', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D064307', 'descriptor_name': 'Microbiota', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D017207', 'descriptor_name': 'Rats, Sprague-Dawley', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1021/jf502557f', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S134644764', 'display_name': 'Journal of Agricultural and Food Chemistry', 'issn_l': '0021-8561', 'issn': ['0021-8561', '1520-5118'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320006', 'host_organization_name': 'American Chemical Society', 'host_organization_lineage': ['https://openalex.org/P4310320006'], 'host_organization_lineage_names': ['American Chemical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/25257195', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [{'funder': 'https://openalex.org/F4320322014', 'funder_display_name': 'Ministry of Food and Drug Safety', 'award_id': '09172KFDA996'}, {'funder': 'https://openalex.org/F4320322120', 'funder_display_name': 'National Research Foundation of Korea', 'award_id': 'NRF- 2014R1A1A1A05002840'}], 'datasets': [], 'versions': [], 'referenced_works_count': 30, 'referenced_works': ['https://openalex.org/W15076868', 'https://openalex.org/W1555144605', 'https://openalex.org/W1912346445', 'https://openalex.org/W1971037804', 'https://openalex.org/W1983200183', 'https://openalex.org/W1985881220', 'https://openalex.org/W1992430132', 'https://openalex.org/W1992788138', 'https://openalex.org/W1997092129', 'https://openalex.org/W1997518805', 'https://openalex.org/W1999971484', 'https://openalex.org/W2008381318', 'https://openalex.org/W2010172093', 'https://openalex.org/W2010481889', 'https://openalex.org/W2012702883', 'https://openalex.org/W2021351184', 'https://openalex.org/W2032963767', 'https://openalex.org/W2042503457', 'https://openalex.org/W2042630551', 'https://openalex.org/W2050713608', 'https://openalex.org/W2053680606', 'https://openalex.org/W2058606189', 'https://openalex.org/W2065104794', 'https://openalex.org/W2074279004', 'https://openalex.org/W2078470138', 'https://openalex.org/W2080059880', 'https://openalex.org/W2099334148', 'https://openalex.org/W2132179124', 'https://openalex.org/W2133881279', 'https://openalex.org/W2325916659'], 'related_works': ['https://openalex.org/W4391375266', 'https://openalex.org/W4387497383', 'https://openalex.org/W2948807893', 'https://openalex.org/W2899084033', 'https://openalex.org/W2778153218', 'https://openalex.org/W2748952813', 'https://openalex.org/W2527526854', 'https://openalex.org/W2078814861', 'https://openalex.org/W1976181487', 'https://openalex.org/W1531601525'], 'abstract_inverted_index': {'This': [0, 119], 'study': [1], 'investigated': [2], 'the': [3, 9, 68, 71, 102, 108, 116, 124, 128, 132, 139, 147], 'effects': [4], 'of': [5, 11, 22, 27, 50, 90, 111, 127, 131, 149], 'intestinal': [6, 133], 'microbiota': [7, 141], 'on': [8, 146], 'metabolism': [10], 'geniposide': [12, 28, 51, 91, 112], 'by': [13, 39], 'using': [14, 40], 'a': [15, 20], 'rat': [16, 93], 'model': [17], 'treated': [18], 'with': [19], 'mixture': [21], 'antibiotics.': [23], 'The': [24, 45, 88], 'plasma': [25, 47], 'concentration': [26], 'was': [29, 113], 'determined': [30], 'after': [31], 'oral': [32], 'administration': [33], 'in': [34, 52, 92, 101, 115], 'control': [35, 53, 103], 'and': [36, 54, 61, 67, 79, 97, 104], 'antibiotics-treated': [37, 55, 105, 117], 'rats': [38, 56], 'liquid': [41], 'chromatography-tandem': [42], 'mass': [43], 'spectrometry.': [44], 'maximum': [46], 'concentrations': [48], '(Cmax)': [49], 'were': [57, 75, 95], '0.91': [58], '±': [59, 63, 77, 81], '0.26': [60], '1.01': [62], '0.04': [64], 'μg/mL,': [65], 'respectively,': [66, 100], 'area': [69], 'under': [70], 'curve': [72], '(AUC)': [73], 'values': [74], '7.34': [76], '3.32': [78], '11.9': [80], '2.1': [82], 'μg·h/mL': [83], '(p': [84], '<': [85], '0.05),': [86], 'respectively.': [87], 'levels': [89], 'feces': [94], '0.64': [96], '15.6': [98], 'mg,': [99], 'groups.': [106], 'Thus,': [107], 'systemic': [109], 'exposure': [110], 'greater': [114], 'rats.': [118], 'may': [120, 142], 'be': [121], 'due': [122], 'to': [123], 'antibiotic-induced': [125], 'suppression': [126], 'metabolic': [129], 'activities': [130], 'microbiota.': [134], 'These': [135], 'results': [136], 'suggest': [137], 'that': [138], 'gut': [140], 'have': [143], 'an': [144], 'impact': [145], 'bioavailability': [148], 'geniposide.': [150]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2328293836', 'counts_by_year': [{'year': 2024, 'cited_by_count': 4}, {'year': 2023, 'cited_by_count': 4}, {'year': 2022, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 4}, {'year': 2019, 'cited_by_count': 3}, {'year': 2018, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 4}, {'year': 2014, 'cited_by_count': 1}], 'updated_date': '2024-12-13T17:26:44.105870', 'created_date': '2016-06-24'}