Title: Lewis Acid Assisted Brønsted Acid Catalyzed Asymmetric Protonation Reaction
Abstract:Despite the increasing use of Brønsted acids in catalysis, application of these catalysts is often restricted due to lower reactivities compared to Lewis acid catalysts. The authors here use a Lewis ...Despite the increasing use of Brønsted acids in catalysis, application of these catalysts is often restricted due to lower reactivities compared to Lewis acid catalysts. The authors here use a Lewis acid assisted Brønsted acid (LBA) system to increase the reactivity of the Brønsted acid, and apply the catalyst nicely to the asymmetric protonation of silyl enol ethers of 2-substituted cyclic ketones. The Lewis base tolerance allows for a catalytic reaction, which was previously unattainable with LBA systems.Read More
Publication Year: 2010
Publication Date: 2010-12-21
Language: en
Type: article
Indexed In: ['crossref']
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